A hybrid of 1-deoxynojirimycin and benzotriazole induces preferential inhibition of butyrylcholinesterase (BuChE) over acetylcholinesterase (AChE)
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DOI: 10.1080/14756366.2022.2117912
Abstract: Abstract The synthesis of four heterodimers in which the copper(I)-catalysed azide-alkyne cycloaddition was employed to connect a 1-deoxynojirimycin moiety with a benzotriazole scaffold is reported. The heterodimers were investigated as inhibitors against acetylcholinesterase (AChE) and… read more here.
Keywords: acetylcholinesterase ache; buche; benzotriazole; preferential inhibition ... See more keywords