Preferential precipitation of acidic variants from monoclonal antibody pools
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DOI: 10.1002/bit.28257
Abstract: Microheterogeneity of monoclonal antibodies (mAbs) can impact their activity and stability. Formation of charge variants is considered as the most important source of the microheterogeneity. In particular, controlling the content of the acidic species is… read more here.
Keywords: precipitation acidic; preferential precipitation; acidic variants; variants monoclonal ... See more keywords