The prefoldin complex stabilizes the von Hippel-Lindau protein against aggregation and degradation
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DOI: 10.1371/journal.pgen.1009183
Abstract: Loss of von Hippel-Lindau protein pVHL function promotes VHL diseases, including sporadic and inherited clear cell Renal Cell Carcinoma (ccRCC). Mechanisms controlling pVHL function and regulation, including folding and stability, remain elusive. Here, we have… read more here.
Keywords: protein; pvhl; prefoldin complex; hippel lindau ... See more keywords