Preformulation studies for nortriptyline
Sign Up to like & getrecommendations! Published in 2017 at "Journal of Thermal Analysis and Calorimetry"
DOI: 10.1007/s10973-017-6269-5
Abstract: Nortriptyline (NRT), usually conditioned as hydrochloride, is a second-generation tricyclic antidepressant that is primarily used as a treatment option for major depression and chronic pain. In this study, a compatibility evaluation between an active pharmaceutical… read more here.
Keywords: binary mixtures; studies nortriptyline; analysis; preformulation studies ... See more keywords
Preformulation Studies of Ezetimibe-Simvastatin Solid Dispersions in the Development of Fixed-Dose Combinations
Sign Up to like & getrecommendations! Published in 2022 at "Pharmaceutics"
DOI: 10.3390/pharmaceutics14050912
Abstract: Two active pharmaceutical ingredients (APIs) with limited solubility, simvastatin and ezetimibe, prepared as a drug-drug solid dispersion (SD) was evaluated for physicochemical, microstructural, and aqueous dissolution properties. The simvastatin-ezetimibe SD was prepared using the co-grinding… read more here.
Keywords: ezetimibe simvastatin; development; fixed dose; preformulation studies ... See more keywords