Association of Generalized Anxiety Disorder With Autonomic Hypersensitivity and Blunted Ventromedial Prefrontal Cortex Activity During Peripheral Adrenergic Stimulation
Sign Up to like & getrecommendations! Published in 2022 at "JAMA Psychiatry"
DOI: 10.1001/jamapsychiatry.2021.4225
Abstract: Key Points Question Do individuals with generalized anxiety disorder (GAD) show abnormal physiological, perceptual, or neural responses during peripheral β-adrenergic stimulation that may indicate interoceptive dysfunction? Findings In this crossover randomized clinical trial, female patients… read more here.
Keywords: ventromedial prefrontal; adrenergic stimulation; generalized anxiety; prefrontal cortex ... See more keywords
Enhanced Social Dominance and Altered Neuronal Excitability in the Prefrontal Cortex of Male KCC2b Mutant Mice
Sign Up to like & getrecommendations! Published in 2019 at "Autism Research"
DOI: 10.1002/aur.2098
Abstract: The K‐Cl cotransporter KCC2 is essential in the development of the “GABA switch” that produces a change in neuronal responses to GABA signaling from excitatory to inhibitory early in brain development, and alterations in this… read more here.
Keywords: autism; social dominance; mice; dominance ... See more keywords
Altered medial prefrontal cortex and dorsal raphé activity predict genotype and correlate with abnormal learning behavior in a mouse model of autism‐associated 2p16.3 deletion
Sign Up to like & getrecommendations! Published in 2022 at "Autism Research"
DOI: 10.1002/aur.2685
Abstract: 2p16.3 deletion, involving NEUREXIN1 (NRXN1) heterozygous deletion, substantially increases the risk of developing autism and other neurodevelopmental disorders. We have a poor understanding of how NRXN1 heterozygosity impacts on brain function and cognition to increase… read more here.
Keywords: 2p16 deletion; deletion; autism; nrxn1 mice ... See more keywords
Neuroticism and conscientiousness respectively positively and negatively correlated with the network characteristic path length in dorsal lateral prefrontal cortex: A resting‐state fNIRS study
Sign Up to like & getrecommendations! Published in 2018 at "Brain and Behavior"
DOI: 10.1002/brb3.1074
Abstract: Accumulating evidence shows that the dorsal lateral prefrontal cortex (dlPFC) is implicated in personality traits. In this study, resting‐state functional near infrared spectroscopy (fNIRS) combined with small‐world analysis was utilized to examine the relationship between… read more here.
Keywords: dorsal lateral; lateral prefrontal; resting state; prefrontal cortex ... See more keywords
Change in emotional self‐concept following socio‐cognitive training relates to structural plasticity of the prefrontal cortex
Sign Up to like & getrecommendations! Published in 2018 at "Brain and Behavior"
DOI: 10.1002/brb3.940
Abstract: Self‐referential processing is a key component of the emotional self‐concept. Previous studies have shown that emotional self‐referential processing is related to structure and function of cortical midline areas such as medial prefrontal cortex (mPFC), and… read more here.
Keywords: training; emotional self; self; self concept ... See more keywords
Positive effects of running exercise on astrocytes in the medial prefrontal cortex in an animal model of depression
Sign Up to like & getrecommendations! Published in 2022 at "Journal of Comparative Neurology"
DOI: 10.1002/cne.25397
Abstract: Depression is one of the most common mental illnesses and seriously affects all aspects of life. Running exercise has been suggested to prevent or alleviate the occurrence and development of depression; however, the underlying mechanisms… read more here.
Keywords: depression; medial prefrontal; prefrontal cortex; effects running ... See more keywords
Early adolescent stress‐induced changes in prefrontal cortex miRNA‐135a and hippocampal miRNA‐16 in male rats
Sign Up to like & getrecommendations! Published in 2017 at "Developmental Psychobiology"
DOI: 10.1002/dev.21558
Abstract: Early-life stress increases susceptibility to post-traumatic stress disorders (PTSD), in which the dysfunction of 5-hydroxytryptamine plays an important role. miRNA-135a in the prefrontal cortex (PFC) and miRNA-16 in the hippocampus (HIP) are closely related to… read more here.
Keywords: adolescent stress; stress; expression; early adolescent ... See more keywords
Prefrontal cortex NG2 glia undergo a developmental switch in their responsiveness to exercise
Sign Up to like & getrecommendations! Published in 2018 at "Developmental Neurobiology"
DOI: 10.1002/dneu.22590
Abstract: Aerobic exercise is known to influence brain function, e.g., enhancing executive function in both children and adults, with many of these influences being attributed to alterations in neurogenesis and neuronal function. Yet oligodendroglia in adult… read more here.
Keywords: cortex ng2; pfc; exercise; young adults ... See more keywords
Early lesion of the reticular thalamic nucleus disrupts the structure and function of the mediodorsal thalamus and prefrontal cortex
Sign Up to like & getrecommendations! Published in 2020 at "Developmental Neurobiology"
DOI: 10.1002/dneu.22733
Abstract: The thalamic reticular nucleus (TRN), part of the thalamus, is a thin GABAergic cell layer adjacent to the relay nuclei of the dorsal thalamus. It receives input from the cortex and other thalamic nuclei and… read more here.
Keywords: thalamic nucleus; trn; early lesion; lesion ... See more keywords
Differential responses of the dorsomedial prefrontal cortex and right posterior superior temporal sulcus to spontaneous mentalizing
Sign Up to like & getrecommendations! Published in 2017 at "Human Brain Mapping"
DOI: 10.1002/hbm.23626
Abstract: Previous research suggests a role of the dorsomedial prefrontal cortex (dmPFC) in metacognitive representation of social information, while the right posterior superior temporal sulcus (pSTS) has been linked to social perception. This study targeted these… read more here.
Keywords: cortex; right posterior; spontaneous mentalizing; posterior superior ... See more keywords
Anticipating control over aversive stimuli is mediated by the medial prefrontal cortex: An fMRI study with healthy adults
Sign Up to like & getrecommendations! Published in 2021 at "Human Brain Mapping"
DOI: 10.1002/hbm.25549
Abstract: The anticipation of control over aversive events in life is relevant for our mental health. Insights on the underlying neural mechanisms remain limited. We developed a new functional magnetic resonance imaging (fMRI) task that uses… read more here.
Keywords: healthy adults; control aversive; cortex; control ... See more keywords