Women With Pregnancy and Lactation–Associated Osteoporosis (PLO) Have Low Bone Remodeling Rates at the Tissue Level
Sign Up to like & getrecommendations! Published in 2019 at "Journal of Bone and Mineral Research"
DOI: 10.1002/jbmr.3750
Abstract: Pregnancy and lactation–associated osteoporosis (PLO) is a rare, severe, early form of osteoporosis in which young women present with fractures, usually multiple vertebral fractures, during late pregnancy or lactation. In studies of idiopathic osteoporosis (IOP)… read more here.
Keywords: women plo; bone; pregnancy; pregnancy lactation ... See more keywords
A review of pregnancy and lactation postmarketing studies required by the FDA
Sign Up to like & getrecommendations! Published in 2022 at "Pharmacoepidemiology and Drug Safety"
DOI: 10.1002/pds.5572
Abstract: Since pregnant and lactating women have historically been excluded from drug development trials, safety studies need to be conducted postapproval. This study evaluated FDA's Post Marketing Requirements for pregnancy and lactation studies from 2007 to… read more here.
Keywords: safety; pregnancy lactation; pregnancy; study ... See more keywords
25-Hydroxyvitamin D profiles and maternal bone mass during pregnancy and lactation in Japanese women
Sign Up to like & getrecommendations! Published in 2019 at "Journal of Bone and Mineral Metabolism"
DOI: 10.1007/s00774-019-01032-w
Abstract: Vitamin D deficiency is observed worldwide and represents a health hazard for mothers, infants and elderly persons. We know that many young Japanese women experience vitamin D insufficiency; however, there is a lack of knowledge… read more here.
Keywords: bone mass; japanese women; pregnancy lactation;
Relevant genetic variants are common in women with pregnancy and lactation-associated osteoporosis (PLO) and predispose to more severe clinical manifestations.
Sign Up to like & getrecommendations! Published in 2021 at "Bone"
DOI: 10.1016/j.bone.2021.115911
Abstract: Pregnancy and lactation-associated osteoporosis (PLO) is a rare skeletal disorder characterized by early-onset osteoporosis typically manifestating with vertebral compression fractures or transient osteoporosis of the hip. We hypothesized that genetic variants may play a role… read more here.
Keywords: pregnancy lactation; genetic variants; bone; plo ... See more keywords
A case of pregnancy and lactation associated osteoporosis in the third pregnancy; robust response to teriparatide despite delayed administration
Sign Up to like & getrecommendations! Published in 2020 at "Bone Reports"
DOI: 10.1016/j.bonr.2020.100706
Abstract: Background Pregnancy and lactation associated osteoporosis (PLO) is a rare condition that may present with fragility fractures occurring for the first time in pregnancy or postpartum period while breastfeeding. Here, we report a rare case… read more here.
Keywords: pregnancy; pregnancy lactation; lactation associated; associated osteoporosis ... See more keywords
Sleep pharmacotherapy for common sleep disorders in pregnancy and lactation.
Sign Up to like & getrecommendations! Published in 2019 at "Chest"
DOI: 10.1016/j.chest.2019.09.026
Abstract: Sleep disturbances are common in pregnancy, and sleep disorders may worsen or present de novo in the course of gestation. Managing a pregnant patient is complicated by the risk of teratogenicity, pharmacokinetic changes, and the… read more here.
Keywords: disorders pregnancy; pregnancy; pregnancy lactation; condition ... See more keywords
Tocilizumab for coronavirus disease 2019 in pregnancy and lactation: a narrative review
Sign Up to like & getrecommendations! Published in 2021 at "Clinical Microbiology and Infection"
DOI: 10.1016/j.cmi.2021.08.016
Abstract: Background Tocilizumab is a monoclonal antibody that interrupts interleukin-6 signaling, reducing downstream effects on inflammation and the innate immune response. It was shown to reduce mortality in patients with severe or critical COVID-19. Pregnant and… read more here.
Keywords: tocilizumab pregnancy; data tocilizumab; pregnancy; pregnancy lactation ... See more keywords
A review of the safety of cosmetic procedures during pregnancy and lactation
Sign Up to like & getrecommendations! Published in 2017 at "International Journal of Women's Dermatology"
DOI: 10.1016/j.ijwd.2017.01.005
Abstract: The safety of cosmetic procedures in patients who are pregnant and/or lactating is a complex clinical question surrounded by uncertainty. Our objective is to consolidate data on the safety of commonly requested cosmetic procedures during… read more here.
Keywords: safety cosmetic; procedures pregnancy; pregnancy lactation; cosmetic procedures ... See more keywords
Mitochondrial pharmacotherapy during pregnancy and lactation in an ADPKD mouse model: a win for both mothers and their offspring.
Sign Up to like & getrecommendations! Published in 2022 at "Kidney international"
DOI: 10.1016/j.kint.2022.02.008
Abstract: Pharmacotherapies that are safe during pregnancy are lacking for patients with autosomal dominant polycystic kidney disease. In this issue, Daneshgar et al. reveal that administration of the mitochondrial-protective peptide, elamipretide, during pregnancy and lactation in a… read more here.
Keywords: mouse model; pregnancy; pregnancy lactation;
Maternal intake of fructose or artificial sweetener during pregnancy and lactation has persistent effects on metabolic and reproductive health of dams post-weaning
Sign Up to like & getrecommendations! Published in 2022 at "Journal of Developmental Origins of Health and Disease"
DOI: 10.1017/s2040174422000022
Abstract: Abstract As rates of obesity, diabetes, and related comorbidities have increased, the consumption of artificial sweeteners (ASs) as sugar substitutes has also risen in popularity as they are perceived as a healthier alternative to sugar… read more here.
Keywords: health; metabolic reproductive; pregnancy lactation; intake ... See more keywords
Maternal high-fat diet consumption during pregnancy and lactation predisposes offspring to renal and metabolic injury later in life: comparative study of diets with different lipid contents
Sign Up to like & getrecommendations! Published in 2022 at "Journal of Developmental Origins of Health and Disease"
DOI: 10.1017/s2040174422000241
Abstract: Abstract Accumulating evidence suggests that maternal overnutrition can result in a higher development risk of obesity and renal disease in the offspring’s adulthood. The present study tested different lipid levels in the maternal diet during… read more here.
Keywords: different lipid; pregnancy lactation; high fat; study ... See more keywords