Dual effect of nifedipine on pregnant human myometrium contractility: Implication of TRPC1
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DOI: 10.1002/jcp.30666
Abstract: Nifedipine, an L‐type voltage‐gated Ca2+ channel (L‐VGCC) blocker, is one of the most used tocolytics to treat preterm labor. In clinical practice, nifedipine efficiently decreases uterine contractions, but its efficacy is limited over time, and… read more here.
Keywords: pregnant human; implication trpc1; effect; nifedipine ... See more keywords
Anoctamin Channels in Human Myometrium: A Novel Target for Tocolysis
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DOI: 10.1177/1933719118757683
Abstract: Background: Spontaneous preterm labor leading to preterm birth is a significant obstetric problem leading to neonatal morbidity and mortality. Current tocolytics are not completely effective and novel targets may afford a therapeutic benefit. Objective: To… read more here.
Keywords: ano family; target tocolysis; novel target; pregnant human ... See more keywords