High‐resolution diffusion MRI studies of development in pregnant mice visualized by novel spatiotemporal encoding schemes
Sign Up to like & getrecommendations! Published in 2019 at "NMR in Biomedicine"
DOI: 10.1002/nbm.4208
Abstract: This study introduces an MRI approach to map diffusion of water in vivo with high resolution under challenging conditions; the approach's potential is then used in diffusivity characterizations of embryos and fetoplacental units in pregnant… read more here.
Keywords: high resolution; resolution diffusion; diffusion; pregnant mice ... See more keywords
Establishment of a model of Neospora caninum infection in pregnant mice.
Sign Up to like & getrecommendations! Published in 2020 at "Parasitology research"
DOI: 10.1007/s00436-020-06903-0
Abstract: The aim of this study was to establish an animal model of Neospora caninum infection in pregnant BALB/c mice infected with different doses of N. caninum tachyzoites. After infection, the female BALB/c mice were housed… read more here.
Keywords: pregnant mice; model; caninum infection; mice ... See more keywords
Porphyromonas gingivalis induces exacerbated periodontal disease during pregnancy.
Sign Up to like & getrecommendations! Published in 2018 at "Microbial pathogenesis"
DOI: 10.1016/j.micpath.2018.08.019
Abstract: Although pregnant women are prone to gingival inflammation, its mechanism remains unclear. Animal models are ideal for investigating immunological mechanisms in the periodontal disease. A murine model for ligature-induced periodontal disease has been modified and… read more here.
Keywords: periodontal disease; pregnancy; inflammation; disease ... See more keywords
Kidney microRNA profile in pregnant mice reveals molecular insights into kidney adaptation to pregnancy: A pilot study
Sign Up to like & getrecommendations! Published in 2019 at "Molecular Genetics and Metabolism Reports"
DOI: 10.1016/j.ymgmr.2019.100486
Abstract: The maternal kidneys undergo numerous physiological changes during pregnancy to maintain a healthy pregnancy for mother and child. Over the past decade, interest in microRNAs (miRNAs) for regulating gene expression during pregnancy has expanded. However,… read more here.
Keywords: pregnancy; study; expression; pregnant mice ... See more keywords
Dose and Diet - Sources of Arsenic Intake in Mouse in Utero Exposure Scenarios.
Sign Up to like & getrecommendations! Published in 2018 at "Chemical research in toxicology"
DOI: 10.1021/acs.chemrestox.7b00309
Abstract: In humans, early life exposure to inorganic arsenic is associated with adverse health effects. Inorganic arsenic in utero or in early postnatal life also produces adverse health effects in offspring of pregnant mice that consumed… read more here.
Keywords: exposure; inorganic arsenic; per billion; pregnant mice ... See more keywords
Metabolomics and Data-Driven Bioinformatics Revealed Key Maternal Metabolites Related to Fetal Lethality via Di(2-ethylhexyl)phthalate Exposure in Pregnant Mice
Sign Up to like & getrecommendations! Published in 2022 at "ACS Omega"
DOI: 10.1021/acsomega.2c02338
Abstract: We performed serum metabolome analysis of di(2-ethylhexyl)phthalate (DEHP)-exposed and control pregnant mice. Pregnant mice (n = 5) were fed a DEHP-containing diet (0.1% or 0.2% DEHP) or a normal diet (control) from gestational days 0–18.… read more here.
Keywords: pregnant mice; exposure; fetal lethality; dehp ... See more keywords
Transfer of convalescent serum to pregnant mice prevents Zika virus infection and microcephaly in offspring
Sign Up to like & getrecommendations! Published in 2017 at "Cell Research"
DOI: 10.1038/cr.2016.144
Abstract: Transfer of convalescent serum to pregnant mice prevents Zika virus infection and microcephaly in offspring read more here.
Keywords: mice prevents; prevents zika; convalescent serum; serum pregnant ... See more keywords
Rapid onset of severe septic shock in the pregnant mouse†
Sign Up to like & getrecommendations! Published in 2018 at "Biology of Reproduction"
DOI: 10.1093/biolre/ioy193
Abstract: Abstract Aims: Globally, sepsis is a major cause of mortality through the combination of cardiovascular collapse and multiorgan dysfunction. Pregnancy appears to increase the risk of death in sepsis, but the exact reason for the… read more here.
Keywords: sepsis; mortality; severe septic; pregnant mice ... See more keywords
Pregnancy Increases Norbuprenorphine Clearance in Mice by Induction of Hepatic Glucuronidation
Sign Up to like & getrecommendations! Published in 2018 at "Drug Metabolism and Disposition"
DOI: 10.1124/dmd.117.076745
Abstract: Norbuprenorphine (NBUP) is the major active metabolite of buprenorphine (BUP) that is commonly used to treat opiate addiction during pregnancy; it possesses 25% of BUP’s analgesic activity and 10 times BUP’s respiratory depression effect. To… read more here.
Keywords: pregnancy; induction hepatic; liver; nonpregnant mice ... See more keywords
Abstract MP14: Endothelial Mineralocorticoid Receptor Deletion Abrogates Leptin-induced Endothelial Dysfunction And Fetal Growth Restriction In Pregnant Mice
Sign Up to like & getrecommendations! Published in 2020 at "Hypertension"
DOI: 10.1161/hyp.76.suppl_1.mp14
Abstract: Obesity increases preeclampsia (PE) risk. Plasma leptin levels increase with body weight in women with PE, and in addition, placental ischemia, an initiating event of PE, also increases plasma leptin. Our lab has shown that… read more here.
Keywords: ecmr ecmr; leptin; ecmr leptin; pregnant mice ... See more keywords
Bile Acids and Tryptophan Metabolism Are Novel Pathways Involved in Metabolic Abnormalities in BPA-Exposed Pregnant Mice and Male Offspring
Sign Up to like & getrecommendations! Published in 2017 at "Endocrinology"
DOI: 10.1210/en.2017-00046
Abstract: Increasing evidence has demonstrated that exposure to endocrine-disrupting chemicals impacts maternal and fetal health, but the underlying mechanisms are still unclear. We previously showed that dietary exposure to 10 µg/kg body weight (bw)/d and 10… read more here.
Keywords: bpa exposed; metabolism; metabolic abnormalities; male offspring ... See more keywords