Uteroplacental and Fetal 4D Flow MRI in the Pregnant Rhesus Macaque
Sign Up to like & getrecommendations! Published in 2019 at "Journal of Magnetic Resonance Imaging"
DOI: 10.1002/jmri.26206
Abstract: Pregnancy complications are often associated with poor uteroplacental vascular adaptation and standard diagnostics are unable to reliably quantify flow in all uteroplacental vessels and have poor sensitivity early in gestation. read more here.
Keywords: fetal flow; mri pregnant; flow mri; uteroplacental fetal ... See more keywords
African-Lineage Zika Virus Replication Dynamics and Maternal-Fetal Interface Infection in Pregnant Rhesus Macaques
Sign Up to like & getrecommendations! Published in 2021 at "Journal of Virology"
DOI: 10.1128/jvi.02220-20
Abstract: ZIKV was first identified in 1947 in Africa, but most of our knowledge of ZIKV is based on studies of the distinct Asian genetic lineage, which caused the outbreak in the Americas in 2015 to… read more here.
Keywords: lineage; pregnant rhesus; african lineage; lineage isolates ... See more keywords
Human immune globulin treatment controls Zika viremia in pregnant rhesus macaques
Sign Up to like & getrecommendations! Published in 2022 at "PLoS ONE"
DOI: 10.1371/journal.pone.0266664
Abstract: There are currently no approved drugs to treat Zika virus (ZIKV) infection during pregnancy. Hyperimmune globulin products such as VARIZIG and WinRho are FDA-approved to treat conditions during pregnancy such as Varicella Zoster virus infection… read more here.
Keywords: pregnant rhesus; immune globulin; human immune; globulin ... See more keywords
Highly efficient maternal-fetal Zika virus transmission in pregnant rhesus macaques
Sign Up to like & getrecommendations! Published in 2017 at "PLoS Pathogens"
DOI: 10.1371/journal.ppat.1006378
Abstract: Infection with Zika virus (ZIKV) is associated with human congenital fetal anomalies. To model fetal outcomes in nonhuman primates, we administered Asian-lineage ZIKV subcutaneously to four pregnant rhesus macaques. While non-pregnant animals in a previous… read more here.
Keywords: pregnant rhesus; transmission; rhesus macaques; maternal fetal ... See more keywords