Articles with "pregnenolone" as a keyword



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Cross‐talk between neurosteroid and endocannabinoid systems in cannabis addiction

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Published in 2022 at "Journal of Neuroendocrinology"

DOI: 10.1111/jne.13191

Abstract: Steroids and endocannabinoids are part of two modulatory systems and some evidence has shown their interconnections in several functions. Homeostasis is a common steady‐state described in the body, which is settled by regulatory systems to… read more here.

Keywords: neurosteroid endocannabinoid; cross talk; pregnenolone; systems cannabis ... See more keywords
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The effect of progesterone and pregnenolone on diabetes status in Chinese rural population: a dose-response analysis from Henan Rural Cohort.

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Published in 2019 at "European journal of endocrinology"

DOI: 10.1530/eje-19-0352

Abstract: OBJECTIVE Previous studies have uncovered a progestin-only contraceptive association with an increased risk of diabetes, but limited study has explored the relationship of endogenous progesterone and pregnenolone level with diabetes status. A case-control study was… read more here.

Keywords: progesterone pregnenolone; pregnenolone; dose response; chinese rural ... See more keywords
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Genomic and non-genomic effects of progesterone and pregnenolone on the function of bovine endometrial cells.

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Published in 2018 at "Veterinarni Medicina"

DOI: 10.17221/58/2009-vetmed

Abstract: Progesterone (P 4 ) decreases oxytocin (OT)-stimulated prostaglandin (PG)F 2α , but not PGE 2 secre- tion from bovine endometrial cells and this effect is partly elicited via a non-genomic route. The aim of this… read more here.

Keywords: genomic non; non genomic; endometrial cells; pregnenolone ... See more keywords
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Pregnenolone protects the liver against doxorubicin-induced cellular injury by anti-inflammatory, antioxidant, and antiapoptotic mechanisms: role of Keap1/Nrf2/HO-1 and P-glycoprotein.

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Published in 2023 at "European review for medical and pharmacological sciences"

DOI: 10.26355/eurrev_202305_32484

Abstract: OBJECTIVE Doxorubicin (DOX) is a widely used cytotoxic anthracycline antibiotic characterized by increased adverse effects that limit its clinical usefulness. Pregnenolone is a pregnane X receptor (PXR) agonist that increases the expression of xenobiotic transporters… read more here.

Keywords: inflammatory antioxidant; dox; dox induced; pregnenolone ... See more keywords