Single‐cell analysis of nonhuman primate preimplantation development in comparison to humans and mice
Sign Up to like & getrecommendations! Published in 2021 at "Developmental Dynamics"
DOI: 10.1002/dvdy.295
Abstract: Genetic programs underlying preimplantation development and early lineage segregation are highly conserved across mammals. It has been suggested that nonhuman primates would be better model organisms for human embryogenesis, but a limited number of studies… read more here.
Keywords: preimplantation; cell analysis; single cell; preimplantation development ... See more keywords
The blueprint of primate preimplantation development
Sign Up to like & getrecommendations! Published in 2017 at "Mechanisms of Development"
DOI: 10.1016/j.mod.2017.04.107
Abstract: Preimplantation development in rodent and primate establishes the founding cell population of the foetus in the epiblast and segregates two extraembryonic lineages, trophoblast and hypoblast. Most of our current knowledge about these cell-fate decisions is… read more here.
Keywords: cell; development; primate specific; preimplantation development ... See more keywords
Berberine alleviates LPS-induced apoptosis, oxidation, and skewed lineages during mouse preimplantation development
Sign Up to like & getrecommendations! Published in 2022 at "Biology of Reproduction"
DOI: 10.1093/biolre/ioac002
Abstract: Abstract Female infertility is a heterogeneous disorder with a variety of complex causes, including inflammation and oxidative stress, which are also closely associated with the pathogenesis of polycystic ovary syndrome (PCOS). As a new treatment… read more here.
Keywords: preimplantation development; apoptosis; development; lps induced ... See more keywords
Regulation of H3K9me3 during preimplantation development†
Sign Up to like & getrecommendations! Published in 2018 at "Biology of Reproduction"
DOI: 10.1093/biolre/ioy201
Abstract: Department of Integrated Biosciences, Graduate School of Frontier Sciences, The University of Tokyo, Kashiwa, Chiba, Japan ∗Correspondence: Department of Integrated Biosciences, Graduate School of Frontier Sciences, The University of Tokyo, Room 302, Shinryoiki-Seimei Building, 5-1-5… read more here.
Keywords: regulation h3k9me3; biology; preimplantation development; h3k9me3 preimplantation ... See more keywords
Chromatin dynamics through mouse preimplantation development revealed by single molecule localisation microscopy
Sign Up to like & getrecommendations! Published in 2022 at "Biology Open"
DOI: 10.1242/bio.059401
Abstract: ABSTRACT Most studies addressing chromatin behaviour during preimplantation development are based on biochemical assays that lack spatial and cell-specific information, crucial during early development. Here, we describe the changes in chromatin taking place at the… read more here.
Keywords: preimplantation development; chromatin dynamics; microscopy; chromatin ... See more keywords
Cortical softening elicits zygotic contractility during mouse preimplantation development
Sign Up to like & getrecommendations! Published in 2022 at "PLoS Biology"
DOI: 10.1371/journal.pbio.3001593
Abstract: Actomyosin contractility is a major engine of preimplantation morphogenesis, which starts at the 8-cell stage during mouse embryonic development. Contractility becomes first visible with the appearance of periodic cortical waves of contraction (PeCoWaCo), which travel… read more here.
Keywords: preimplantation development; cell; contractility; contractility mouse ... See more keywords
Histone remodeling reflects conserved mechanisms of bovine and human preimplantation development
Sign Up to like & getrecommendations! Published in 2023 at "EMBO reports"
DOI: 10.15252/embr.202255726
Abstract: How histone modifications regulate changes in gene expression during preimplantation development in any species remains poorly understood. Using CUT&Tag to overcome limiting amounts of biological material, we profiled two activating (H3K4me3 and H3K27ac) and two… read more here.
Keywords: preimplantation development; preimplantation; human preimplantation; histone remodeling ... See more keywords
Reverse Transcriptase Affects Gametogenesis and Preimplantation Development in Mouse
Sign Up to like & getrecommendations! Published in 2020 at "In Vivo"
DOI: 10.21873/invivo.12037
Abstract: Background/Aim: The expression of reverse transcriptase (RT) in ovaries, testes, gametes and embryos highlights its critical role in cell growth and differentiation. We sought to investigate the effects of the potent RT inhibitor lamivudine in… read more here.
Keywords: reverse transcriptase; development; mouse; preimplantation development ... See more keywords
Multiscale analysis of single and double maternal-zygotic Myh9 and Myh10 mutants during mouse preimplantation development
Sign Up to like & getrecommendations! Published in 2021 at "eLife"
DOI: 10.7554/elife.68536
Abstract: During the first days of mammalian development, the embryo forms the blastocyst, the structure responsible for implanting the mammalian embryo. Consisting of an epithelium enveloping the pluripotent inner cell mass and a fluid-filled lumen, the… read more here.
Keywords: development; maternal zygotic; single double; preimplantation development ... See more keywords