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Published in 2019 at "JCI Insight"
DOI: 10.1172/jci.insight.126315
Abstract: Cardiomyopathies are complex heart muscle diseases that can be inherited or acquired. Dilated cardiomyopathy can result from mutations in LMNA, encoding the nuclear intermediate filament proteins lamin A/C. Some LMNA mutations lead to accumulation of…
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Keywords:
accumulation;
mediates myocardial;
prelamin mediates;
inflammation ... See more keywords