Design, Synthesis, And Preliminary Bioactivity Evaluation Of 2,7-Substituted Carbazole Derivatives As Potent Autotaxin Inhibitors And Antitumor Agents.
Sign Up to like & getrecommendations! Published in 2018 at "Anti-cancer agents in medicinal chemistry"
DOI: 10.2174/1871520618666180830161821
Abstract: BACKGROUND Autotaxin-LPA signaling has been implicated in cancer progression, and targeted for the discovery of cancer therapeutic agents. OBJECTIVE Potential ATX inhibitors were synthesized to develop novel leading compounds and effective anticancer agents. METHOD The… read more here.
Keywords: design synthesis; bioactivity evaluation; preliminary bioactivity; synthesis preliminary ... See more keywords
Preliminary Bioactivity Assessment of Myrothecium Species (Stachybotryaceae) Crude Extracts against Aedes aegypti (Diptera: Culicidae): A First Approach from This Phytopathogenic Fungi
Sign Up to like & getrecommendations! Published in 2024 at "Journal of Fungi"
DOI: 10.3390/jof10070466
Abstract: Mosquitoes, as insect vectors, play a crucial role in transmitting viruses and parasites, leading to millions of human deaths in tropical and subtropical regions worldwide. This study aimed to evaluate the effects of ethanolic extracts… read more here.
Keywords: fungi preliminary; aedes aegypti; preliminary bioactivity; mosquito larvae ... See more keywords