Design, Synthesis, And Preliminary Bioactivity Evaluation Of 2,7-Substituted Carbazole Derivatives As Potent Autotaxin Inhibitors And Antitumor Agents.
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DOI: 10.2174/1871520618666180830161821
Abstract: BACKGROUND Autotaxin-LPA signaling has been implicated in cancer progression, and targeted for the discovery of cancer therapeutic agents. OBJECTIVE Potential ATX inhibitors were synthesized to develop novel leading compounds and effective anticancer agents. METHOD The… read more here.
Keywords: design synthesis; bioactivity evaluation; preliminary bioactivity; synthesis preliminary ... See more keywords