Home‐Based Tele‐tDCS in Amyotrophic Lateral Sclerosis: Feasibility, Safety, and Preliminary Efficacy
Sign Up to like & getrecommendations! Published in 2025 at "Annals of Clinical and Translational Neurology"
DOI: 10.1002/acn3.70038
Abstract: Amyotrophic lateral sclerosis (ALS) is a progressive neurodegenerative disease with limited treatment options. Transcranial direct current stimulation (tDCS) shows promise as a neuromodulatory intervention in various neurological disorders, but its application in ALS, particularly in… read more here.
Keywords: home based; safety preliminary; amyotrophic lateral; feasibility safety ... See more keywords
Phase I pharmacokinetic, safety, and preliminary efficacy study of tiragolumab in combination with atezolizumab in Chinese patients with advanced solid tumors
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DOI: 10.1007/s00280-024-04650-y
Abstract: Tiragolumab is an immunoglobulin G1 monoclonal antibody targeting the immune checkpoint T cell immunoreceptor with immunoglobulin and immunoreceptor ITIM domains. Targeting multiple immune pathways may improve anti-tumor responses. The phase I YP42514 study assessed the… read more here.
Keywords: chinese patients; atezolizumab chinese; safety preliminary; safety ... See more keywords
Brief Report: Feasibility and Preliminary Efficacy of a Behavioral Intervention for Minimally Verbal Girls with Autism Spectrum Disorder
Sign Up to like & getrecommendations! Published in 2019 at "Journal of Autism and Developmental Disorders"
DOI: 10.1007/s10803-018-03872-3
Abstract: We report the feasibility and preliminary efficacy of a structured behavioral intervention with a sample of minimally verbal girls with autism spectrum disorder between the ages of 2 and 6 years old. Ten participants with… read more here.
Keywords: behavioral intervention; autism; preliminary efficacy; feasibility ... See more keywords
Feasibility and preliminary efficacy of an intervention to reduce older adults’ sedentary behavior
Sign Up to like & getrecommendations! Published in 2017 at "Translational Behavioral Medicine"
DOI: 10.1007/s13142-016-0394-8
Abstract: Older adults represent the segment of the population that sits the most. This study evaluated the feasibility, acceptability, safety, and preliminary efficacy of an intervention to reduce sedentary behavior (SB) in older adults that can… read more here.
Keywords: intervention; week; preliminary efficacy; content ... See more keywords
Photorealistic Avatar and Teen Physical Activity: Feasibility and Preliminary Efficacy
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DOI: 10.1089/g4h.2017.0103
Abstract: Abstract Objective: Exergames played with a photorealistic avatar may enhance motivation to play, in addition to frequency, duration, and intensity of game-play. This article reports the feasibility and preliminary efficacy of an exergame played with… read more here.
Keywords: avatar; preliminary efficacy; photorealistic avatar; feasibility preliminary ... See more keywords
Pharmacokinetics, immunogenicity, safety, and preliminary efficacy of subcutaneous turoctocog alfa pegol in previously treated patients with severe hemophilia A (alleviate 1)
Sign Up to like & getrecommendations! Published in 2019 at "Journal of Thrombosis and Haemostasis"
DOI: 10.1111/jth.14660
Abstract: The current standard of care for patients with hemophilia A is regular prophylaxis with factor VIII (FVIII) administered intravenously. Interest in subcutaneous (s.c.) administration, to potentially increase convenience, reduce the treatment burden and improve compliance,… read more here.
Keywords: subcutaneous turoctocog; preliminary efficacy; efficacy subcutaneous; immunogenicity safety ... See more keywords
Feasibility and Preliminary Efficacy of Isradipine During Outpatient Buprenorphine Stabilization and Detoxification: A Pilot Randomized, Placebo-Controlled Trial
Sign Up to like & getrecommendations! Published in 2020 at "Substance Abuse: Research and Treatment"
DOI: 10.1177/1178221820970926
Abstract: Background: Given the immense burden of the widespread use of opioids around the world, exploring treatments that improve drug use outcomes, and craving and withdrawal measures in individuals with opioid use disorder is crucial. This… read more here.
Keywords: stabilization; trial; preliminary efficacy; pilot ... See more keywords
Treatment response and preliminary efficacy of hepatic tumour laser ablation under the guidance of percutaneous and endoscopic ultrasonography
Sign Up to like & getrecommendations! Published in 2019 at "World Journal of Surgical Oncology"
DOI: 10.1186/s12957-019-1677-6
Abstract: BackgroundStudies focusing on the treatment effectiveness of endoscopic ultrasonography (EUS)-guided laser ablation (LA) for hepatic tumours or the technical differences from percutaneous ultrasonography (US)-guided LA are lacking. The objective of this study was to evaluate… read more here.
Keywords: treatment response; preliminary efficacy; ablation; treatment ... See more keywords
Safety and preliminary efficacy of EIK1001 in combination with pembrolizumab in participants with advanced solid tumors.
Sign Up to like & getrecommendations! Published in 2024 at "Journal of Clinical Oncology"
DOI: 10.1200/jco.2024.42.16_suppl.2521
Abstract: 2521 Background: Immune checkpoint inhibitors (ICIs) relieve immunosuppression of tumor-reactive T cells and enhance antitumor immune response; however, not all patients benefit and some become refractory. EIK1001 is a Toll-like receptor (TLR)7/8 agonist that stimulates… read more here.
Keywords: pembrolizumab; combination; combination pembrolizumab; safety ... See more keywords
Development and Preliminary Efficacy of a Mindfulness-Based Counseling Program as Part of Comprehensive Cardiac Rehabilitation: A Pilot Study
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DOI: 10.17547/kjsr.2024.32.2.53
Abstract: Background: While psychological intervention is recognized as a core component of cardiac rehabilitation (CR), its application in CR remains limited. This study aimed to develop a psychological counseling program (the Mindfulness-Based Counseling Program [MBCP]) as… read more here.
Keywords: counseling program; program; mindfulness; study ... See more keywords