Articles with "premanifest manifest" as a keyword



Computerised Dynamic Posturography in Premanifest and Manifest individuals with Huntington’s Disease

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Published in 2018 at "Scientific Reports"

DOI: 10.1038/s41598-018-32924-y

Abstract: Evidence from small-scale studies indicates that impairments in postural stability are an early and disabling feature of Huntington’s disease (HD) and may be a useful clinical endpoint for disease modifying trials. Larger studies are needed… read more here.

Keywords: huntington disease; disease; dynamic posturography; postural stability ... See more keywords

Revealing the Timeline of Structural MRI Changes in Premanifest to Manifest Huntington Disease

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Published in 2021 at "Neurology: Genetics"

DOI: 10.1212/nxg.0000000000000617

Abstract: Background and Objectives Longitudinal measurements of brain atrophy using structural MRI (sMRI) can provide powerful markers for tracking disease progression in neurodegenerative diseases. In this study, we use a disease progression model to learn individual-level… read more here.

Keywords: disease progression; huntington disease; premanifest manifest; error years ... See more keywords