CSNK1a1 Regulates PRMT1 to Maintain the Progenitor State in Self-Renewing Somatic Tissue.
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DOI: 10.1016/j.devcel.2017.08.021
Abstract: Somatic progenitors sustain tissue self-renewal while suppressing premature differentiation. Protein arginine methyltransferases (PRMTs) affect many processes; however, their role in progenitor function is incompletely understood. PRMT1 was found to be the most highly expressed PRMT… read more here.
Keywords: csnk1a1; premature differentiation; tissue; prmt1 ... See more keywords
Recent Zika Virus Isolates Induce Premature Differentiation of Neural Progenitors in Human Brain Organoids.
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DOI: 10.1016/j.stem.2016.12.005
Abstract: The recent Zika virus (ZIKV) epidemic is associated with microcephaly in newborns. Although the connection between ZIKV and neurodevelopmental defects is widely recognized, the underlying mechanisms are poorly understood. Here we show that two recently… read more here.
Keywords: premature differentiation; recent zika; brain organoids; differentiation neural ... See more keywords