Phoenixin‐14 Alleviates Premature Ovarian Failure by Inhibiting Ferroptosis Through SLC7A11/GPX4
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DOI: 10.1002/ddr.70110
Abstract: Premature ovarian failure (POF) is a complex condition marked by early ovarian decline, reduced follicular reserve, and compromised oocyte quality. Oxidative stress (OS) and ferroptosis are critical drivers of POF progression. This study investigates the… read more here.
Keywords: pnx; ferroptosis; premature ovarian; slc7a11 gpx4 ... See more keywords
Effects of Environment and Lifestyle Factors on Premature Ovarian Failure.
Sign Up to like & getrecommendations! Published in 2021 at "Advances in experimental medicine and biology"
DOI: 10.1007/978-981-33-4187-6_4
Abstract: Premature ovarian insufficiency (POI) or primary ovarian failure is defined as a cessation of the menstrual cycle in women younger than 40 years old. It is strictly defined as more than 4 months of oligomenorrhea or amenorrhea… read more here.
Keywords: effects environment; ovarian failure; premature ovarian; lifestyle factors ... See more keywords
Gene variants identified by whole-exome sequencing in 33 French women with premature ovarian insufficiency
Sign Up to like & getrecommendations! Published in 2018 at "Journal of Assisted Reproduction and Genetics"
DOI: 10.1007/s10815-018-1349-4
Abstract: PurposeTo investigate the potential genetic etiology of premature ovarian insufficiency (POI).MethodsWhole-exome sequencing (WES) was done on DNA samples from women diagnosed with POI. Mutations identified were analyzed by in silico tools and were annotated according… read more here.
Keywords: premature ovarian; exome sequencing; ovarian insufficiency; gene variants ... See more keywords
Osteoporosis and premature ovarian insufficiency: geographic variation in clinicians’ and consumers’ knowledge gaps and barriers to care
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DOI: 10.1007/s11657-020-00713-8
Abstract: Purpose To determine whether geographic variation exists in osteoporosis knowledge, management, and barriers to care in the setting of premature ovarian insufficiency (POI), among general practitioners (GPs) and women with POI. Methods Australian GPs completed… read more here.
Keywords: osteoporosis knowledge; geographic variation; barriers care; premature ovarian ... See more keywords
Serum biomarker analysis in patients with premature ovarian insufficiency.
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DOI: 10.1016/j.cyto.2019.154876
Abstract: Premature ovarian insufficiency (POI) is a primary ovarian defect characterized by premature depletion of ovarian follicles before 40 years of age. The disorder has been attributed to various causes, but the study of altered proteins in… read more here.
Keywords: serum; serum biomarker; ovarian insufficiency; premature ovarian ... See more keywords
Effect of Jiajian Guishen Formula on the senescence-associated heterochromatic foci in mouse ovaria after induction of premature ovarian aging by the endocrine-disrupting agent 4-vinylcyclohexene diepoxide.
Sign Up to like & getrecommendations! Published in 2020 at "Journal of ethnopharmacology"
DOI: 10.1016/j.jep.2020.113720
Abstract: ETHNOPHARMACOLOGICAL RELEVANCE Jiajian Guishen Formula (JJGSF), which is a prescription of Traditional Chinese Medicine (TCM), has been reported to be useful in the treatment of premature ovarian insufficiency (POI). AIM OF THE STUDY To investigate… read more here.
Keywords: jjgsf; jiajian guishen; endocrine disrupting; group ... See more keywords
Analysis of NR5A1 in 142 patients with premature ovarian insufficiency, diminished ovarian reserve, or unexplained infertility.
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DOI: 10.1016/j.maturitas.2019.10.011
Abstract: Ovarian deficiency, including diminished ovarian reserve and premature ovarian insufficiency, represents one of the main causes of female infertility. Little is known of the genetic basis of diminished ovarian reserve, while premature ovarian insufficiency often… read more here.
Keywords: premature ovarian; diminished ovarian; ovarian reserve; ovarian insufficiency ... See more keywords
Modulatory effect of quercetin on premature ovarian insufficiency induced by cyclophosphamide via the PARP1 and GSK3β
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DOI: 10.1038/s41598-025-21397-5
Abstract: Premature ovarian insufficiency (POI) is a significant side effect of cyclophosphamide (CTX) chemotherapy in women, leading to early ovarian dysfunction. Quercetin (QR), a flavonoid with antioxidant and anti-apoptotic properties, has shown potential in mitigating ovarian… read more here.
Keywords: premature ovarian; ovarian insufficiency; pharmacology; effect ... See more keywords
Premature ovarian failure, short stature, and Hashimoto’s disease in an 18-year-old adolescent girl with 46, X, i(X)(q10)
Sign Up to like & getrecommendations! Published in 2018 at "Gynecological Endocrinology"
DOI: 10.1080/09513590.2018.1464137
Abstract: Abstract Premature ovarian failure (POF) is a heterogeneous condition affecting girls and women. We detected a previously healthy 18-year-old adolescent girl, presented with amenorrhea over six months, as well as circulating levels of estradiol lower… read more here.
Keywords: hashimoto disease; old adolescent; disease; premature ovarian ... See more keywords
Endometrium receptivity in premature ovarian insufficiency – how to improve fertility rate and predict diseases?
Sign Up to like & getrecommendations! Published in 2018 at "Gynecological Endocrinology"
DOI: 10.1080/09513590.2018.1490715
Abstract: Abstract More empathized approach is required and is obligatory to women with premature ovarian insufficiency (POI) interested for pregnancy. In order to improve fertility rate in POI patients our suggestions would be: (1) To decrease… read more here.
Keywords: fertility rate; improve fertility; ovarian insufficiency; premature ovarian ... See more keywords
A case of premature ovarian insufficiency in Nijmegen breakage syndrome patient and review of literature. From gene mutation to clinical management
Sign Up to like & getrecommendations! Published in 2019 at "Gynecological Endocrinology"
DOI: 10.1080/09513590.2019.1626366
Abstract: Abstract Background: Nijmegen breakage syndrome (NBS) is an autosomal recessive disorder leading to chromosomal instability and an array of symptoms, including characteristic facial features (bird-like face), predisposition to malignancies, as well as hypergonadotropic hypogonadism. This… read more here.
Keywords: nijmegen breakage; breakage syndrome; management; ovarian insufficiency ... See more keywords