Prenatal alcohol exposure induced congenital heart diseases: From bench to bedside
Sign Up to like & getrecommendations! Published in 2020 at "Birth Defects Research"
DOI: 10.1002/bdr2.1743
Abstract: Alcohol consumption is increasing worldwide. Many child‐bearing‐aged women consume alcohol during pregnancy, intentionally or unintentionally, thereby increasing the potential risk for severe congenital diseases. Congenital heart disease (CHD) is the most common birth defect worldwide… read more here.
Keywords: alcohol exposure; prenatal alcohol; congenital heart; alcohol ... See more keywords
Prenatal alcohol exposure can be determined from baby teeth: Proof of concept
Sign Up to like & getrecommendations! Published in 2022 at "Birth Defects Research"
DOI: 10.1002/bdr2.2054
Abstract: Prenatal alcohol exposure (PAE), leading to fetal alcohol spectrum disorders (FASD), is a serious public health issue in the United States and globally. Diagnosis of FASD is crucial in obtaining appropriate care, but it is… read more here.
Keywords: alcohol exposure; exposure determined; alcohol; determined baby ... See more keywords
Hippocampal neurogenesis in the C57BL/6J mice at early adulthood following prenatal alcohol exposure
Sign Up to like & getrecommendations! Published in 2017 at "Metabolic Brain Disease"
DOI: 10.1007/s11011-017-0156-4
Abstract: We examined the effect of chronic prenatal alcohol exposure (PAE) on the process of adult neurogenesis in C57BL/6J mice at early adulthood (PND 56). Pregnant mice, and their in utero litters, were exposed to alcohol,… read more here.
Keywords: prenatal alcohol; c57bl mice; neurogenesis c57bl; mice early ... See more keywords
Long-term alterations to DNA methylation as a biomarker of prenatal alcohol exposure: From mouse models to human children with fetal alcohol spectrum disorders.
Sign Up to like & getrecommendations! Published in 2017 at "Alcohol"
DOI: 10.1016/j.alcohol.2016.11.009
Abstract: Rodent models of Fetal Alcohol Spectrum Disorders (FASD) have revealed that prenatal alcohol exposure (PAE) results in differential DNA cytosine methylation in the developing brain. The resulting genome-wide methylation changes are enriched in genes with… read more here.
Keywords: prenatal alcohol; methylation; spectrum disorders; fetal alcohol ... See more keywords
Moderate prenatal alcohol exposure alters the number and function of GABAergic interneurons in the murine orbitofrontal cortex.
Sign Up to like & getrecommendations! Published in 2020 at "Alcohol"
DOI: 10.1016/j.alcohol.2020.06.001
Abstract: Exposure to alcohol during development produces Fetal Alcohol Spectrum Disorders (FASD), characterized by a wide range of effects that include deficits in multiple cognitive domains. Early identification and treatment of individuals with FASD remains a… read more here.
Keywords: prenatal alcohol; function; exposure; moderate prenatal ... See more keywords
Prenatal alcohol exposure and facial morphology in a UK cohort.
Sign Up to like & getrecommendations! Published in 2019 at "Drug and alcohol dependence"
DOI: 10.1016/j.drugalcdep.2018.11.031
Abstract: BACKGROUND High levels of prenatal alcohol exposure are known to cause an array of adverse outcomes including fetal alcohol syndrome (FAS); however, the effects of low to moderate exposure are less-well characterized. Previous findings suggest… read more here.
Keywords: prenatal alcohol; facial morphology; exposure; alcohol exposure ... See more keywords
Associations of prenatal alcohol exposure and offspring harmful alcohol use: findings from the Raine Study.
Sign Up to like & getrecommendations! Published in 2020 at "Drug and alcohol dependence"
DOI: 10.1016/j.drugalcdep.2020.108305
Abstract: BACKGROUND Epidemiological evidence suggests offspring exposed to prenatal alcohol are at increased risk of alcohol use disorders in adulthood. The evidence on the risk of developing harmful alcohol use in adolescence is less clear. METHODS… read more here.
Keywords: prenatal alcohol; exposure; harmful alcohol; alcohol ... See more keywords
Cell-type and fetal-sex-specific targets of prenatal alcohol exposure in developing mouse cerebral cortex
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DOI: 10.1016/j.isci.2021.102439
Abstract: Summary Prenatal alcohol exposure (PAE) results in cerebral cortical dysgenesis. Single-cell RNA sequencing was performed on murine fetal cerebral cortical cells from six timed pregnancies, to decipher persistent cell- and sex-specific effects of an episode… read more here.
Keywords: prenatal alcohol; sex specific; sex; alcohol exposure ... See more keywords
Moderate prenatal alcohol exposure suppresses the TLR4-mediated innate immune response in the hippocampus of young rats
Sign Up to like & getrecommendations! Published in 2019 at "Neuroscience Letters"
DOI: 10.1016/j.neulet.2019.01.049
Abstract: Prenatal alcohol exposure (PAE) could lead to developmental disorders of the central nervous system (CNS) and mental retardation. Toll-like receptor (TLR) 4 plays an important role in PAE-induced neurodevelopmental defects. However, how PAE affects TLR4… read more here.
Keywords: prenatal alcohol; response; pae; alcohol exposure ... See more keywords
Prenatal alcohol exposure and offspring alcohol use and misuse at 22 years of age: A prospective longitudinal study.
Sign Up to like & getrecommendations! Published in 2019 at "Neurotoxicology and teratology"
DOI: 10.1016/j.ntt.2018.11.001
Abstract: Studies have shown that prenatal alcohol exposure (PAE) is related to drinking problems during adulthood, but the level of prenatal exposure associated with young adults' quantity and frequency of alcohol use and drinking problems has… read more here.
Keywords: prenatal alcohol; age; exposure; alcohol ... See more keywords
Prenatal alcohol and tobacco exposures and the risk of cannabis use in offspring: Findings from a population-based cohort study.
Sign Up to like & getrecommendations! Published in 2022 at "Neurotoxicology and teratology"
DOI: 10.1016/j.ntt.2022.107064
Abstract: BACKGROUND There is a paucity of prospective longitudinal studies examining the associations between maternal use of alcohol and tobacco during pregnancy and the risk of cannabis use in offspring. The aim of this study was… read more here.
Keywords: alcohol tobacco; cannabis use; alcohol; use ... See more keywords