Association of Prenatal Exposure to Endocrine-Disrupting Chemicals With Liver Injury in Children
Sign Up to like & getrecommendations! Published in 2022 at "JAMA Network Open"
DOI: 10.1001/jamanetworkopen.2022.20176
Abstract: Key Points Question Is prenatal exposure to endocrine-disrupting chemicals (EDCs) associated with liver injury and hepatocellular apoptosis in school-aged children? Findings In the Human Early-Life Exposome population-based cohort study of 1108 mother-child pairs from 6… read more here.
Keywords: liver injury; exposure endocrine; prenatal exposure; disrupting chemicals ... See more keywords
Analysis of Prenatal Exposure to Opioid Analgesics and Scholastic Skills in Children in Fifth Grade in Norway
Sign Up to like & getrecommendations! Published in 2022 at "JAMA Network Open"
DOI: 10.1001/jamanetworkopen.2022.22425
Abstract: Key Points Question Is there an association between prenatal exposure to opioid analgesics and fifth-grade scholastic skills? Findings In this cohort study of 64 256 children, exposure to opioid analgesics in the first trimester or… read more here.
Keywords: exposure; opioid analgesics; scholastic skills; prenatal exposure ... See more keywords
Prenatal Exposure to Antiseizure Medications and Risk of Epilepsy in Children of Mothers With Epilepsy
Sign Up to like & getrecommendations! Published in 2024 at "JAMA Network Open"
DOI: 10.1001/jamanetworkopen.2023.56425
Abstract: Key Points Question Is use of antiseizure medication in pregnancy among mothers with epilepsy associated with epilepsy risk in their children? Findings In this cohort study of 38 663 children of mothers with epilepsy, there was… read more here.
Keywords: antiseizure; risk epilepsy; mothers epilepsy; prenatal exposure ... See more keywords
Prenatal Exposure to Valproic Acid Across Various Indications for Use
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DOI: 10.1001/jamanetworkopen.2024.12680
Abstract: Key Points Question Are US Food and Drug Administration warnings to prevent prenatal exposure to valproic acid associated with changes in pregnancy risk and contraceptive use across indications? Findings In this cohort study of 165 772… read more here.
Keywords: acid; valproic acid; prenatal exposure; exposure valproic ... See more keywords
Prenatal Exposure to Ambient Air Pollution and Cerebral Palsy
Sign Up to like & getrecommendations! Published in 2024 at "JAMA Network Open"
DOI: 10.1001/jamanetworkopen.2024.20717
Abstract: This cohort study evaluates the association between prenatal exposure to ambient air pollution and risk of cerebral palsy in a cohort of children residing in Canada and born at term gestation. read more here.
Keywords: cerebral palsy; air pollution; prenatal exposure; ambient air ... See more keywords
Prenatal Exposure to Antiseizure Medication and Incidence of Childhood- and Adolescence-Onset Psychiatric Disorders.
Sign Up to like & getrecommendations! Published in 2023 at "JAMA neurology"
DOI: 10.1001/jamaneurol.2023.0674
Abstract: Importance Prenatal antiseizure medication (ASM) exposure has been associated with adverse early neurodevelopment, but associations with a wider range of psychiatric end points have not been studied. Objective To examine the association between prenatal exposure… read more here.
Keywords: psychiatric disorders; antiseizure medication; childhood adolescence; prenatal exposure ... See more keywords
Unraveling Hypothalamus‐Pituitary dysregulation: Hypergonadotropism in F1 progeny due to prenatal exposure to hexavalent chromium
Sign Up to like & getrecommendations! Published in 2024 at "Journal of Biochemical and Molecular Toxicology"
DOI: 10.1002/jbt.23699
Abstract: The endocrine disruptor hexavalent chromium [Cr(VI)] is a proven reproductive toxicant. We recently demonstrated that prenatal Cr(VI) exposure causes testicular resistance to gonadotropins, resulting in hypergonadotropic hypoandrogenism in F1 rats. However, the mechanism driving hypergonadotropism… read more here.
Keywords: receptor; hexavalent chromium; hypergonadotropism; gnrh ... See more keywords
Prenatal Exposure to Acetaminophen and Overweight in Childhood
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DOI: 10.1002/oby.22526
Abstract: Acetaminophen (paracetamol), a medication commonly used in pregnancy, has hormonal effects, as has been suggested in experimental studies. Developmental exposure to endocrine disruptors could predispose individuals to weight gain. This study evaluated the associations between… read more here.
Keywords: prenatal exposure; overweight childhood; exposure acetaminophen; exposure ... See more keywords
Prenatal exposure to non‐steroidal anti‐inflammatory drugs and risk of attention‐deficit/hyperactivity disorder: A follow‐up study in the Norwegian mother, father and child cohort
Sign Up to like & getrecommendations! Published in 2021 at "Pharmacoepidemiology and Drug Safety"
DOI: 10.1002/pds.5250
Abstract: To estimate the association between Attention‐Deficit/Hyperactivity Disorder (ADHD) in children in preschool and primary school, and prenatal exposure to non‐steroidal anti‐inflammatory drugs (NSAIDs) by timing and duration. read more here.
Keywords: exposure non; prenatal exposure; deficit hyperactivity; hyperactivity disorder ... See more keywords
Effect of prenatal exposure to Benzo[a]pyrene on ovarian toxicity and reproductive dysfunction: Protective effect of atorvastatin in the embryonic period
Sign Up to like & getrecommendations! Published in 2021 at "Environmental Toxicology"
DOI: 10.1002/tox.23164
Abstract: As an environmental contaminant, Benzo[a]pyrene (B[a]P; BaP) disrupts the antioxidant signaling and thus leads to the induction of oxidative stress and the damage of DNA in the ovary. low‐dose atorvastatin (ATV) has antioxidant and anti‐apoptotic… read more here.
Keywords: effect; benzo pyrene; ovarian toxicity; prenatal exposure ... See more keywords
Distinct epigenetic modulation of differentially expressed genes in the adult mouse brain following prenatal exposure to low-dose bisphenol A
Sign Up to like & getrecommendations! Published in 2024 at "Cell Biology and Toxicology"
DOI: 10.1007/s10565-024-09875-4
Abstract: Bisphenol A (BPA) is a common component in the manufacture of daily plastic consumer goods. Recent studies have suggested that prenatal exposure to BPA can increase the susceptibility of offspring to mental illness, although the… read more here.
Keywords: adult mouse; bpa; mouse brain; exposure ... See more keywords