Prenatal inflammation perturbs murine fetal hematopoietic development and causes persistent changes to postnatal immunity
Sign Up to like & getrecommendations! Published in 2022 at "Cell reports"
DOI: 10.1101/2022.05.08.491095
Abstract: Adult hematopoietic stem and progenitor cells (HSPCs) respond directly to inflammation and infection, resulting in both acute and persistent changes to quiescence, mobilization, and differentiation. Here we show that fetal HSPCs respond to prenatal inflammation… read more here.
Keywords: inflammation; prenatal inflammation; development; immunity ... See more keywords
Long-Term Environmental Enrichment Relieves Dysfunctional Cognition and Synaptic Protein Levels Induced by Prenatal Inflammation in Older CD-1 Mice
Sign Up to like & getrecommendations! Published in 2022 at "Neural Plasticity"
DOI: 10.1155/2022/1483101
Abstract: A mounting body of evidence suggests that prenatal inflammation may enhance the rate of age-associated cognitive decline and may involve aberrant amounts of synaptic proteins in the hippocampus, including synaptotagmin-1 (Syt1) and activity-regulated cytoskeleton-associated protein… read more here.
Keywords: inflammation; prenatal inflammation; environmental enrichment; age ... See more keywords