Antitrypanosomal and antileishmanial activity of prenyl-1,2,3-triazoles.
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DOI: 10.1039/c7md00008a
Abstract: A series of prenyl 1,2,3-triazoles were prepared from isoprenyl azides and different alkynes. The dipolar cycloaddition reaction provided exclusively primary azide products as regioisomeric mixtures that were separated by column chromatography and fully characterized. Most… read more here.
Keywords: antitrypanosomal antileishmanial; prenyl triazoles; activity prenyl; prenyl ... See more keywords
Catalytic prenyl conjugate additions for synthesis of enantiomerically enriched PPAPs
Sign Up to like & getrecommendations! Published in 2024 at "Science"
DOI: 10.1126/science.adr8612
Abstract: Polycyclic polyprenylated acylphloroglucinols (PPAPs) are a class of >400 natural products with a broad spectrum of bioactivity, ranging from antidepressant and antimicrobial to anti-obesity and anticancer activity. Here, we present a scalable, regio-, site-, and… read more here.
Keywords: prenyl conjugate; additions synthesis; prenyl; catalytic prenyl ... See more keywords