Articles with "prenylated quinolinecarboxylic" as a keyword



Prenylated quinolinecarboxylic acid derivative prevents neuronal cell death through inhibition of MKK4

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Published in 2019 at "Biochemical Pharmacology"

DOI: 10.1016/j.bcp.2018.10.008

Abstract: &NA; The development of neuroprotective agents is necessary for the treatment of neurodegenerative diseases. Here, we report PQA‐11, a prenylated quinolinecarboxylic acid (PQA) derivative, as a potent neuroprotectant. PQA‐11 inhibits glutamate‐induced cell death and caspase‐3… read more here.

Keywords: prenylated quinolinecarboxylic; pqa; mkk4; cell death ... See more keywords