Venous thromboembolism during preoperative chemotherapy in the CRITICS gastric cancer trial
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DOI: 10.1002/cam4.3118
Abstract: The occurrence of a venous thromboembolism (VTE) is common in patients with cancer. Gastric cancer has been associated with one of the highest risks for VTE. Chemotherapy, especially cisplatin has been associated with a high… read more here.
Keywords: chemotherapy critics; gastric cancer; venous thromboembolism; preoperative chemotherapy ... See more keywords
The effect of preoperative chemotherapy treatment in surgically treated intrahepatic cholangiocarcinoma patients—A multi‐institutional analysis
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DOI: 10.1002/jso.24524
Abstract: While preoperative chemotherapy (pCT) is utilized in many intra‐abdominal cancers, the use of pCT among patients with intrahepatic cholangiocarcinoma (ICC) remains ill defined. As such, the objective of the current study was to examine the… read more here.
Keywords: intrahepatic cholangiocarcinoma; effect preoperative; preoperative chemotherapy; chemotherapy treatment ... See more keywords
Preoperative Chemotherapy May Not Influence the Remnant Liver Regenerations and Outcomes After Hepatectomy for Colorectal Liver Metastasis
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DOI: 10.1007/s00268-018-4590-1
Abstract: BackgroundVarious chemotherapy regimens have been shown to improve outcomes when administered before tumor excision surgery. However, there is no consensus on the utility of multidisciplinary treatment with preoperative chemotherapy for treating colorectal liver metastasis (CLM).Materials… read more here.
Keywords: chemotherapy; remnant liver; colorectal liver; liver ... See more keywords
Tumor and serum DNA methylation in women receiving preoperative chemotherapy with or without vorinostat in TBCRC008
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DOI: 10.1007/s10549-017-4503-2
Abstract: BackgroundMethylated gene markers have shown promise in predicting breast cancer outcomes and treatment response. We evaluated whether baseline and changes in tissue and serum methylation levels would predict pathological complete response (pCR) in patients with… read more here.
Keywords: cmi; methylation; preoperative chemotherapy; breast cancer ... See more keywords
Comparison of Perioperative and Survival Outcomes of Laparoscopic Versus Open Gastrectomy after Preoperative Chemotherapy: a Propensity Score–Matched Analysis
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DOI: 10.1007/s12262-019-01880-w
Abstract: Comparisons of laparoscopy-assisted gastrectomy (LAG) and open gastrectomy (OG) in the setting of neoadjuvant chemotherapy (NACT) are lacking. A prospectively maintained database of patients with gastric cancer who underwent LAG or OG following NACT from… read more here.
Keywords: chemotherapy; perioperative survival; survival outcomes; preoperative chemotherapy ... See more keywords
Loss of muscle mass during preoperative chemotherapy as a prognosticator for poor survival in patients with colorectal liver metastases☆
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DOI: 10.1016/j.surg.2018.07.031
Abstract: Background: The survival impact of specific body composition changes during preoperative chemotherapy in patients with colorectal liver metastases undergoing curative‐intent surgery remains unclear. This study aimed to determine the impact of changes in body weight… read more here.
Keywords: muscle mass; muscle; preoperative chemotherapy; loss ... See more keywords
Complete pathological response after preoperative chemotherapy for locally advanced rectal cancer: a case report
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DOI: 10.1093/annonc/mdz343.052
Abstract: Abstract Background For locally advanced rectal cancer in Japan, radical surgery including lateral lymph node dissection followed by postoperative chemotherapy is the standard treatment. However, with regard to preoperative chemotherapy for locally advanced rectal cancer,… read more here.
Keywords: rectal cancer; advanced rectal; preoperative chemotherapy; cancer ... See more keywords
Efficacy of Preoperative Chemotherapy in High-Risk Upper Tract Urothelial Carcinoma (UTUC).
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DOI: 10.1097/ju.0000000000000737
Abstract: PURPOSE The impact of preoperative chemotherapy (PC) in patients with upper urinary tract urothelial carcinoma (UTUC) remains poorly investigated. We assessed the rates of pathologic complete response (pCR; pT0N0/X) and downstaging (pDS; ≤pT1N0/X) at radical… read more here.
Keywords: high risk; carcinoma utuc; tract urothelial; preoperative chemotherapy ... See more keywords
Camrelizumab in combination with preoperative chemotherapy for locally advanced esophageal squamous cell carcinoma: A single-arm, open-label, phase II study.
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DOI: 10.1200/jco.2021.39.3_suppl.222
Abstract: 222Background:At present, esophageal cell carcinoma (ESCC) has a dismal prognosis with huge unmet clinical needs. With the potential benefit of combining PD-1 inhibitor with neoadjuvant chemotherap... read more here.
Keywords: cell carcinoma; preoperative chemotherapy; combination preoperative; cell ... See more keywords
Development of a model to predict pathologic response to chemotherapy in patients with colorectal liver metastases.
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DOI: 10.21037/jgo-21-82
Abstract: Background Preoperative chemotherapy has widely been used in colorectal cancer liver metastasis (CRLM). Pathological response to chemotherapy is very important in evaluating tumor biology. However, there is still a lack of a non-invasive and accurate… read more here.
Keywords: chemotherapy; response; preoperative chemotherapy; response chemotherapy ... See more keywords
NQO1 as a Marker of Chemosensitivity and Prognosis for Colorectal Liver Metastasis
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DOI: 10.21873/anticanres.14916
Abstract: Background/Aim: This study aimed to evaluate how NAD(P)H: quinone oxidoreductase-1 (NQO1) affects survival after hepatectomy in patients with colorectal liver metastasis (CRLM). Patients and Methods: A retrospective analysis was conducted of 88 consecutive patients who… read more here.
Keywords: nqo1 marker; colorectal liver; crlm; preoperative chemotherapy ... See more keywords