Preparation of a Ribosomally Synthesized Fungal Peptide Toxin Precursor and its in-vitro Cyclization.
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DOI: 10.1016/j.jbiotec.2019.12.004
Abstract: Amatoxins are ribosomally synthesized and post-translationally modified peptides (RiPPs) found in poisonous mushrooms. These cyclic peptides are potent inhibitors of RNA polymerase II transcriptional activity. Though the macrocyclization of amatoxin is extensively studied, little is… read more here.
Keywords: peptide toxin; fungal peptide; preparation ribosomally; synthesized fungal ... See more keywords