The healthy exocrine pancreas contains preproinsulin-specific CD8 T cells that attack islets in type 1 diabetes
Sign Up to like & getrecommendations! Published in 2020 at "Science Advances"
DOI: 10.1126/sciadv.abc5586
Abstract: Preproinsulin-specific CD8+ T cells residing in the exocrine pancreas become attracted to islets in type 1 diabetes. Preproinsulin (PPI) is presumably a crucial islet autoantigen found in patients with type 1 diabetes (T1D) but is… read more here.
Keywords: specific cd8; cd8; cd8 cells; preproinsulin specific ... See more keywords