Cx26 partial loss causes accelerated presbycusis by redox imbalance and dysregulation of Nfr2 pathway
Sign Up to like & getrecommendations! Published in 2018 at "Redox Biology"
DOI: 10.1016/j.redox.2018.08.002
Abstract: Mutations in GJB2, the gene that encodes connexin 26 (Cx26), are the most common cause of sensorineural hearing impairment. The truncating variant 35delG, which determines a complete loss of Cx26 protein function, is the prevalent… read more here.
Keywords: presbycusis redox; pathway; mice; presbycusis ... See more keywords