CYP2C19 loss of function alleles are not associated with higher prevalence of gastrointestinal bleeds in those who have been prescribed antidepressants: Analysis in a British-South Asian cohort.
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DOI: 10.1111/bcp.15762
Abstract: BACKGROUND CYP2C19 is a hepatic enzyme involved in the metabolism of antidepressants associated with increased gastrointestinal bleed (GIB) risk. The aim of our study is to explore a possible association between loss of function CYP2C19… read more here.
Keywords: metabolizer; loss function; prevalence; cyp2c19 ... See more keywords