Antigen presentation between T cells drives Th17 polarization under conditions of limiting antigen
Sign Up to like & getrecommendations! Published in 2021 at "Cell Reports"
DOI: 10.1016/j.celrep.2021.108861
Abstract: Summary T cells form immunological synapses with professional antigen-presenting cells (APCs) resulting in T cell activation and the acquisition of peptide antigen-MHC (pMHC) complexes from the plasma membrane of the APC. They thus become APCs… read more here.
Keywords: presentation cells; antigen presentation; antigen; cell ... See more keywords
Four pathways of CD1 antigen presentation to T cells.
Sign Up to like & getrecommendations! Published in 2017 at "Current opinion in immunology"
DOI: 10.1016/j.coi.2017.07.013
Abstract: CD1a, CD1b, CD1c and CD1d proteins migrate through distinct subcellular compartments of antigen presenting cells and so can be considered to take four separate pathways leading to display of lipid antigens to T cell receptors.… read more here.
Keywords: presentation cells; cd1 antigen; four pathways; pathways cd1 ... See more keywords
Editing peptide presentation to T cells
Sign Up to like & getrecommendations! Published in 2017 at "Science"
DOI: 10.1126/science.aaq1398
Abstract: Structures reveal how high-affinity peptides are presented to induce immune responses In mammals, two types of major histocompatibility complex (MHC) molecules, MHC I and MHC II, are found on the surface of cells in association… read more here.
Keywords: editing peptide; presentation cells; peptide presentation; mhc ... See more keywords
Pegylation Reduces the Uptake of Certolizumab Pegol by Dendritic Cells and Epitope Presentation to T-Cells
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Immunology"
DOI: 10.3389/fimmu.2022.808606
Abstract: Pegylation of biopharmaceuticals is the most common strategy to increase their half-life in the blood and is associated with a reduced immunogenicity. As antigen presentation is a primary event in the activation of CD4 T-cells… read more here.
Keywords: czp; certolizumab pegol; presentation cells; dendritic cells ... See more keywords