The Importance of Being Presented: Target Validation by Immunopeptidomics for Epitope-Specific Immunotherapies
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DOI: 10.3389/fimmu.2022.883989
Abstract: Presentation of tumor-specific or tumor-associated peptides by HLA class I molecules to CD8+ T cells is the foundation of epitope-centric cancer immunotherapies. While often in silico HLA binding predictions or in vitro immunogenicity assays are… read more here.
Keywords: target validation; importance; importance presented; presented target ... See more keywords