Effect of Sacubitril/Valsartan vs Valsartan on Left Atrial Volume in Patients With Pre–Heart Failure With Preserved Ejection Fraction
Sign Up to like & getrecommendations! Published in 2023 at "JAMA Cardiology"
DOI: 10.1001/jamacardio.2023.0065
Abstract: Key Points Question Can neprilysin inhibition improve markers of cardiovascular structure and function in patients with pre–heart failure with preserved ejection fraction? Findings In this randomized clinical trial of 250 asymptomatic patients, sacubitril/valsartan vs valsartan… read more here.
Keywords: heart failure; preserved ejection; pre heart; failure preserved ... See more keywords
Detyrosinated α‐tubulin mediates mitochondrial dysfunction and diastolic impairment in heart failure with preserved ejection fraction
Sign Up to like & getrecommendations! Published in 2025 at "FEBS Letters"
DOI: 10.1002/1873-3468.70119
Abstract: Heart failure with preserved ejection fraction (HFpEF) is characterized by diastolic dysfunction, yet its molecular basis remains unclear. Here, we identified detyrosinated α‐tubulin as a key cause of mitochondrial dysfunction and impaired mitophagy in HFpEF.… read more here.
Keywords: detyrosinated tubulin; failure preserved; dysfunction; ejection fraction ... See more keywords
Catheter ablation of atrial fibrillation in patients with heart failure and preserved ejection fraction: A meta‐analysis
Sign Up to like & getrecommendations! Published in 2022 at "Clinical Cardiology"
DOI: 10.1002/clc.23841
Abstract: Catheter ablation (CA) is an effective treatment for patients with atrial fibrillation (AF). The potential of CA to benefit AF patients with heart failure and preserved ejection fraction (HFpEF) is uncertain. read more here.
Keywords: heart failure; preserved ejection; failure preserved; patients heart ... See more keywords
The Role of Esaxerenone in the Continuum of Heart Failure With Preserved Ejection Fraction: Insights From a Prospective Observational Study
Sign Up to like & getrecommendations! Published in 2025 at "Clinical Cardiology"
DOI: 10.1002/clc.70137
Abstract: Heart failure with preserved ejection fraction (HFpEF) presents significant therapeutic challenges, particularly exacerbated by comorbidities such as hypertension and diabetes. The modulation of the Renin–Angiotensin–Aldosterone System is critical in managing HFpEF progression. Esaxerenone (ESAX), a… read more here.
Keywords: ejection fraction; heart failure; preserved ejection; failure preserved ... See more keywords
Evaluating the Impact of Catheter Ablation on Cardiovascular and Cerebral Outcomes in Atrial Fibrillation With Heart Failure and Preserved Ejection Fraction
Sign Up to like & getrecommendations! Published in 2025 at "Clinical Cardiology"
DOI: 10.1002/clc.70220
Abstract: Evidence supporting catheter ablation (CA) for atrial fibrillation (AF) in heart failure with preserved ejection fraction (HFpEF) is limited. This study evaluated the impact of CA on clinical outcomes in patients with AF and HFpEF… read more here.
Keywords: fibrillation heart; catheter ablation; failure preserved; heart failure ... See more keywords
Aging and Heart Failure with Preserved Ejection Fraction.
Sign Up to like & getrecommendations! Published in 2022 at "Comprehensive Physiology"
DOI: 10.1002/cphy.c210035
Abstract: Heart failure is a clinical syndrome characterized by the inability of the cardiovascular system to provide adequate cardiac output at normal filling pressures. This results in a clinical syndrome characterized by dyspnea, edema, and decreased… read more here.
Keywords: failure preserved; heart failure; preserved ejection; hfpef ... See more keywords
The renal–cardiac connection in subjects with preserved ejection fraction: a population based study
Sign Up to like & getrecommendations! Published in 2017 at "ESC Heart Failure"
DOI: 10.1002/ehf2.12143
Abstract: Chronic kidney disease (CKD) is prevalent and is associated with increased cardiovascular morbidity and mortality. The interaction between diastolic dysfunction (DD) and CKD in subjects with preserved systolic function is not well defined. This study… read more here.
Keywords: ejection fraction; subjects preserved; renal cardiac; preserved ejection ... See more keywords
Malnutrition in acute heart failure with preserved ejection fraction: clinical correlates and prognostic implications
Sign Up to like & getrecommendations! Published in 2019 at "ESC Heart Failure"
DOI: 10.1002/ehf2.12501
Abstract: This study aimed to evaluate the prognostic significance of nutritional status in post‐discharge Asians with heart failure with preserved ejection fraction (HFpEF). read more here.
Keywords: ejection fraction; failure preserved; heart; heart failure ... See more keywords
The diagnostic and prognostic value of galectin‐3 in patients at risk for heart failure with preserved ejection fraction: results from the DIAST‐CHF study
Sign Up to like & getrecommendations! Published in 2021 at "ESC Heart Failure"
DOI: 10.1002/ehf2.13174
Abstract: Galectin‐3 (Gal‐3) predicts long‐term outcome among patients with heart failure (HF) with preserved ejection fraction (HFpEF). The ability of Gal‐3 to diagnose and predict incident HFpEF in a cohort at risk for HFpEF is of… read more here.
Keywords: ejection fraction; failure preserved; heart; heart failure ... See more keywords
Right atrial pressure represents cumulative cardiac burden in heart failure with preserved ejection fraction
Sign Up to like & getrecommendations! Published in 2022 at "ESC Heart Failure"
DOI: 10.1002/ehf2.13853
Abstract: Right‐sided filling pressure is elevated in some patients with heart failure (HF) and preserved ejection fraction (HFpEF). We hypothesized that right atrial pressure (RAP) would represent the cumulative burden of abnormalities in the left heart,… read more here.
Keywords: heart failure; preserved ejection; failure preserved; pressure ... See more keywords
Targeting efficacy of spironolactone in patients with heart failure with preserved ejection fraction: the TOPCAT study
Sign Up to like & getrecommendations! Published in 2022 at "ESC Heart Failure"
DOI: 10.1002/ehf2.14068
Abstract: We aimed to explore the heterogeneous treatment effects (HTEs) for spironolactone treatment in patients with Heart failure with preserved ejection fraction (HFpEF) and examine the efficacy and safety of spironolactone medication, ensuring a better individualized… read more here.
Keywords: heart failure; preserved ejection; failure preserved; patients heart ... See more keywords