ABCB1 Polymorphisms and Cold Pressor Pain Responses: Opioid-Dependent Patients on Methadone Maintenance Therapy
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DOI: 10.1097/nnr.0000000000000204
Abstract: Background Methadone is a substrate of the P-glycoprotein efflux transporter, which is encoded by ABCB1 (MDR1), and thus, ABCB1 polymorphisms may influence the transport of methadone at the blood–brain barrier, affecting its adverse effects. Objectives… read more here.
Keywords: abcb1 polymorphisms; pressor pain; cold pressor; pain ... See more keywords