Under (Genetic Selection) Pressure: Human Tumors and Human Populations in Hypoxia.
Sign Up to like & getrecommendations! Published in 2025 at "Cancer discovery"
DOI: 10.1158/2159-8290.cd-25-0175
Abstract: Arenillas and colleagues report that pheochromocytomas and paragangliomas in the setting of chronic hypoxia due to cyanotic congenital heart disease harbor, at high frequency, somatic gain-of-function mutations in the EPAS1 gene, which encodes for one… read more here.
Keywords: genetic selection; human tumors; human populations; pressure human ... See more keywords