Deconstructing normal pressure hydrocephalus: Ventriculomegaly as early sign of neurodegeneration
Sign Up to like & getrecommendations! Published in 2017 at "Annals of Neurology"
DOI: 10.1002/ana.25046
Abstract: Idiopathic normal pressure hydrocephalus (NPH) remains both oversuspected on clinical grounds and underconfirmed when based on immediate and sustained response to cerebrospinal fluid diversion. Poor long‐term postshunt benefits and findings of neurodegenerative pathology in most… read more here.
Keywords: normal pressure; deconstructing normal; pressure hydrocephalus; pathology ... See more keywords
Higher prevalence of idiopathic normal pressure hydrocephalus‐like MRI features in progressive supranuclear palsy: An imaging reminder of atypical parkinsonism
Sign Up to like & getrecommendations! Published in 2023 at "Brain and Behavior"
DOI: 10.1002/brb3.2884
Abstract: The classic triad of idiopathic normal pressure hydrocephalus (NPH) encompass gait disturbance, cognitive impairment, and urinary incontinence. These symptoms overlap with parkinsonism but with distinct treatment. Lacking applicable differentiation also hampers the prediction to therapeutic… read more here.
Keywords: normal pressure; hydrocephalus; parkinsonism; pressure hydrocephalus ... See more keywords
Nationwide hospital‐based survey of idiopathic normal pressure hydrocephalus in Japan: Epidemiological and clinical characteristics
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DOI: 10.1002/brb3.635
Abstract: There have been no nationwide epidemiological studies of idiopathic normal pressure hydrocephalus (iNPH) in Japan. Therefore, a nationwide epidemiologic survey of iNPH was performed to determine the number of cases and clinical characteristics by sex… read more here.
Keywords: normal pressure; idiopathic normal; pressure hydrocephalus; clinical characteristics ... See more keywords
Distinct cerebral cortical perfusion patterns in idiopathic normal‐pressure hydrocephalus
Sign Up to like & getrecommendations! Published in 2022 at "Human Brain Mapping"
DOI: 10.1002/hbm.25974
Abstract: The aims of the study are to evaluate idiopathic normal‐pressure hydrocephalus (INPH)‐related cerebral blood flow (CBF) abnormalities and to investigate their relation to cortical thickness in INPH patients. We investigated cortical CBF utilizing surface‐based early‐phase… read more here.
Keywords: normal pressure; healthy controls; inph patients; perfusion ... See more keywords
Editorial for: “ΔADC Analysis of the Brain in Idiopathic Normal Pressure Hydrocephalus Before and After Cerebrospinal Fluid Drainage”
Sign Up to like & getrecommendations! Published in 2020 at "Journal of Magnetic Resonance Imaging"
DOI: 10.1002/jmri.27442
Abstract: Normal pressure hydrocephalus is known as “curable dementia”, since patients might experience a significant improvement of their symptoms after shunt surgery. However, accurate prediction, which patients might benefit from surgery is still challenging due to… read more here.
Keywords: surgery; normal pressure; lumbar tap; pressure hydrocephalus ... See more keywords
Change in Morphological Features of Enlarged Subarachnoid Spaces Following Treatment in Idiopathic Normal Pressure Hydrocephalus
Sign Up to like & getrecommendations! Published in 2022 at "Journal of Magnetic Resonance Imaging"
DOI: 10.1002/jmri.28340
Abstract: Focally enlarged sulci (FES) are areas of proposed extraventricular fluid entrapment that may occur within idiopathic normal pressure hydrocephalus (iNPH) with radiographic evidence of disproportionately enlarged subarachnoid‐space hydrocephalus (DESH), and should be differentiated from atrophy. read more here.
Keywords: normal pressure; enlarged subarachnoid; hydrocephalus; pressure hydrocephalus ... See more keywords
Gaps, Controversies, and Proposed Roadmap for Research in Normal Pressure Hydrocephalus
Sign Up to like & getrecommendations! Published in 2020 at "Movement Disorders"
DOI: 10.1002/mds.28251
Abstract: Idiopathic normal pressure hydrocephalus is considered common but remains underinvestigated. There are no uniformly accepted diagnostic criteria and therapeutic guidelines. We summarize the accumulated evidence regarding the definition, pathophysiology, diagnosis, and treatment of idiopathic normal… read more here.
Keywords: normal pressure; gaps controversies; pressure hydrocephalus; controversies proposed ... See more keywords
MRI Linear Measurements in Normal Pressure Hydrocephalus Versus Progressive Supranuclear Palsy
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DOI: 10.1002/mds.28330
Abstract: Jeffrey H. Kordower, PhD,* Michael S. Okun, MD, and Joseph Jankovic, MD Department of Neurological Sciences, Rush University Medical Center, Chicago, Illinois, USA, Department of Neurology, Norman Fixel Institute for Neurological Diseases, University of Florida… read more here.
Keywords: neurology; linear measurements; mri linear; normal pressure ... See more keywords
Reduced Striatal DAT Uptake Normalizes After Shunt in Normal‐Pressure Hydrocephalus
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DOI: 10.1002/mds.28336
Abstract: Idiopathic normal pressure hydrocephalus (iNPH) is characterized by gait disturbance, cognitive impairment, parkinsonian signs, and urinary incontinence, responsive to shunt surgery. There is evidence that dopamine transporter imaging (DAT-SPECT) is reduced in 30%–60% of iNPH… read more here.
Keywords: normal pressure; pressure hydrocephalus; inph patients; shunt ... See more keywords
Reply to: “MRI Linear Measurements in Normal Pressure Hydrocephalus Versus Progressive Supranuclear Palsy”
Sign Up to like & getrecommendations! Published in 2020 at "Movement Disorders"
DOI: 10.1002/mds.28337
Abstract: We thank Ugga and colleagues for their interest and positive comments on our recent article. We agree that differentiating between idiopathic normal pressure hydrocephalus (iNPH) and progressive supranuclear palsy (PSP) is often challenging and that… read more here.
Keywords: supranuclear palsy; article; psp; normal pressure ... See more keywords
Standardized image evaluation in patients with idiopathic normal pressure hydrocephalus: consistency and reproducibility
Sign Up to like & getrecommendations! Published in 2019 at "Neuroradiology"
DOI: 10.1007/s00234-019-02273-2
Abstract: Assess the agreement for two investigators between computed tomography (CT) and magnetic resonance imaging (MRI) for seven imaging features included in the iNPH Radscale, a radiological screening tool. The study included 35 patients with idiopathic… read more here.
Keywords: normal pressure; idiopathic normal; pressure hydrocephalus; patients idiopathic ... See more keywords