Genetic analysis of over 1 million people identifies 535 new loci associated with blood pressure traits
Sign Up to like & getrecommendations! Published in 2018 at "Nature Genetics"
DOI: 10.1038/s41588-018-0205-x
Abstract: High blood pressure is a highly heritable and modifiable risk factor for cardiovascular disease. We report the largest genetic association study of blood pressure traits (systolic, diastolic and pulse pressure) to date in over 1… read more here.
Keywords: loci; blood pressure; pressure traits; million people ... See more keywords
Genetic predictors of blood pressure traits are associated with preeclampsia
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DOI: 10.1038/s41598-024-68469-6
Abstract: Preeclampsia, a pregnancy complication characterized by hypertension after 20 gestational weeks, is a major cause of maternal and neonatal morbidity and mortality. Mechanisms leading to preeclampsia are unclear; however, there is evidence of high heritability.… read more here.
Keywords: pressure; blood pressure; associated preeclampsia; pressure traits ... See more keywords
Abstract 074: Uncovering Hundreds of New Loci from a Multi-Ancestry Study of Blood Pressure Traits in Over 2.5M Individuals
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DOI: 10.1161/hyp.82.suppl_1.074
Abstract: Introduction: Elevated blood pressure (BP) is a leading contributor to global morbidity and mortality, with notable ancestral and racial differences in BP traits in the United States and globally. To date, most BP genome-wide association… read more here.
Keywords: multi ancestry; pressure traits; ancestry; blood pressure ... See more keywords