Changes in presynaptic calcium signalling accompany age‐related deficits in hippocampal LTP and cognitive impairment
Sign Up to like & getrecommendations! Published in 2019 at "Aging Cell"
DOI: 10.1111/acel.13008
Abstract: The loss of cognitive function accompanying healthy aging is not associated with extensive or characteristic patterns of cell death, suggesting it is caused by more subtle changes in synaptic properties. In the hippocampal CA1 region,… read more here.
Keywords: changes presynaptic; age; presynaptic calcium; impairment ... See more keywords
Imaging and Analysis of Presynaptic Calcium Influx in Cultured Neurons Using synGCaMP6f
Sign Up to like & getrecommendations! Published in 2019 at "Frontiers in Synaptic Neuroscience"
DOI: 10.3389/fnsyn.2019.00012
Abstract: Presynaptic Ca2+ influx through voltage-gated calcium channels (VGCCs) is a key step in synaptic transmission that links action potential (AP)-derived depolarization to vesicle release. However, investigation of presynaptic Ca2+ influx by patch clamp recordings is… read more here.
Keywords: ca2 transients; presynaptic calcium; presynaptic ca2; ca2 ... See more keywords