Pretargeted PET of Osteodestructive Lesions in Dogs.
Sign Up to like & getrecommendations! Published in 2022 at "Molecular pharmaceutics"
DOI: 10.1021/acs.molpharmaceut.2c00220
Abstract: The last decade has witnessed the creation of a highly effective approach to in vivo pretargeting based on the inverse electron demand Diels-Alder (IEDDA) click ligation between tetrazine (Tz) and trans-cyclooctene (TCO). Despite the steady… read more here.
Keywords: 64cu sarar; chemistry; pretargeted pet; tco ... See more keywords
Bioorthogonal Diels–Alder Click Chemistry-Based Pretargeted PET Imaging Strategy for Monitoring Programmed Death-Ligand 1 Expression
Sign Up to like & getrecommendations! Published in 2024 at "ACS Omega"
DOI: 10.1021/acsomega.4c01063
Abstract: The development of antibody tracers for positron emission tomography (PET) imaging enables real-time monitoring of tumor expression of programmed cell death ligand 1 (PD-L1) in vivo, aiming to facilitate the selection of immunotherapy responders. However,… read more here.
Keywords: pet imaging; chemistry; pretargeted pet; imaging strategy ... See more keywords
Development of 18F-Labeled Bispyridyl Tetrazines for In Vivo Pretargeted PET Imaging
Sign Up to like & getrecommendations! Published in 2022 at "Pharmaceuticals"
DOI: 10.3390/ph15020245
Abstract: Pretargeted PET imaging is an emerging and fast-developing method to monitor immuno-oncology strategies. Currently, tetrazine ligation is considered the most promising bioorthogonal reaction for pretargeting in vivo. Recently, we have developed a method to 18F-label… read more here.
Keywords: bispyridyl; pretargeted pet; pet imaging; 18f labeled ... See more keywords