Prevalence of Germline Findings Among Tumors From Cancer Types Lacking Hereditary Testing Guidelines
Sign Up to like & getrecommendations! Published in 2022 at "JAMA Network Open"
DOI: 10.1001/jamanetworkopen.2022.13070
Abstract: Key Points Question What is the prevalence of germline findings in cancers lacking hereditary testing guidelines? Findings In this cross-sectional study including records from 34 642 patients, approximately 7% of patients with cancer harbored pathogenic or… read more here.
Keywords: germline findings; hereditary testing; lacking hereditary; cancer ... See more keywords
Determining the prevalence of germline BAP1 mutations in malignant mesothelioma (MM).
Sign Up to like & getrecommendations! Published in 2017 at "Journal of Clinical Oncology"
DOI: 10.1200/jco.2017.35.15_suppl.e13118
Abstract: e13118Background: Somatic BAP1 mutations are very common in MM tumors (Bueno et al. Nat Genet 2016, Bott et al. Nature Genet 2011) and germline BAP1 mutations have also been shown to segregate in numerous families… read more here.
Keywords: germline bap1; bap1; bap1 mutations; prevalence germline ... See more keywords
Prevalence of Germline Mutations in Cancer Predisposition Genes in Patients with Pancreatic Cancer or Suspected Related Hereditary Syndromes: Historical Prospective Analysis
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DOI: 10.3390/cancers15061852
Abstract: Simple Summary Approximately 5–10% of all pancreatic adenocarcinomas (PDACs) are caused by highly penetrant pathogenic germline variants (PVs). Specific surveillance programs and eventual targeted oncological therapies can be offered to patients carrying some of the… read more here.
Keywords: genes patients; related hereditary; predisposition genes; suspected related ... See more keywords
Erratum: Prevalence of germline BRCA mutations among women with carcinoma of the peritoneum or fallopian tube
Sign Up to like & getrecommendations! Published in 2018 at "Journal of Gynecologic Oncology"
DOI: 10.3802/jgo.2018.29.e80
Abstract: This corrects the article on p. e43 in vol. 29, PMID: 29770616. read more here.
Keywords: erratum prevalence; germline brca; brca mutations; among women ... See more keywords