Dominant epitopes presented by prevalent HLA alleles permit wide use of banked CMVpp65 T cells in adoptive therapy
Sign Up to like & getrecommendations! Published in 2022 at "Blood Advances"
DOI: 10.1182/bloodadvances.2022007005
Abstract: Key Points Dominance of epitopes presented by prevalent HLA alleles permits use of banked CMVpp65CTLs in >90% of transplant recipients. Immunodominant CMVpp65CTLs restricted by HLA B35 alleles fail to lyse infected cells in vitro or… read more here.
Keywords: hla alleles; epitopes presented; prevalent hla; presented prevalent ... See more keywords
Screening and Identification of HBV Epitopes Restricted by Multiple Prevalent HLA-A Allotypes
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Immunology"
DOI: 10.3389/fimmu.2022.847105
Abstract: Although host T cell immune responses to hepatitis B virus (HBV) have been demonstrated to have important influences on the outcome of HBV infection, the development of T cell epitope-based vaccine and T cell therapy… read more here.
Keywords: cell; hla allotypes; hbv; prevalent hla ... See more keywords