The proofreading activity of Pfprex from Plasmodium falciparum can prevent mutagenesis of the apicoplast genome by oxidized nucleotides
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DOI: 10.1038/s41598-020-67853-2
Abstract: The DNA polymerase module of the Pfprex enzyme (PfpPol) is responsible for duplication of the genome of the apicoplast organelle in the malaria parasite. We show that PfpPol can misincorporate oxidized nucleotides such as 8oxodGTP… read more here.
Keywords: apicoplast genome; proofreading activity; prevent mutagenesis; oxidized nucleotides ... See more keywords