Preventing Phosphorylation of the GABAAR β3 Subunit Compromises the Behavioral Effects of Neuroactive Steroids
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DOI: 10.3389/fnmol.2022.817996
Abstract: Neuroactive steroids (NASs) have potent anxiolytic, anticonvulsant, sedative, and hypnotic actions, that reflect in part their efficacy as GABAAR positive allosteric modulators (PAM). In addition to this, NAS exert metabotropic effects on GABAergic inhibition via… read more here.
Keywords: neuroactive steroids; preventing phosphorylation; gabaar subunit; subunit ... See more keywords