Feasibility trial for primary stroke prevention in children with sickle cell anemia in Nigeria (SPIN trial)
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DOI: 10.1002/ajh.24770
Abstract: The vast majority of children with sickle cell anemia (SCA) live in Africa, where evidence‐based guidelines for primary stroke prevention are lacking. In Kano, Nigeria, we conducted a feasibility trial to determine the acceptability of… read more here.
Keywords: trial; primary stroke; prevention children; stroke prevention ... See more keywords
Hydroxyurea for secondary stroke prevention in children with sickle cell anemia in Nigeria: a randomized controlled trial
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DOI: 10.1182/blood.2022016620
Abstract: Key Points • Both low and moderate doses of hydroxyurea are efficacious for secondary stroke prevention in low-resource settings.• The median time between the initial stroke and death was less than a year, 0.8 years… read more here.
Keywords: secondary stroke; prevention children; hydroxyurea secondary; stroke prevention ... See more keywords