Inhibition of p38MAPK signalling prevents epidermal blistering and alterations of desmosome structure induced by pemphigus autoantibodies in human epidermis
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DOI: 10.1111/bjd.15721
Abstract: Pemphigus vulgaris (PV) is a skin blistering disease caused by autoantibodies targeting the desmosomal adhesion proteins desmoglein (Dsg) 3 and 1. The mechanisms underlying pemphigus skin blistering are not fully elucidated but p38 mitogen‐activated protein… read more here.
Keywords: p38mapk signalling; epidermal blistering; signalling prevents; inhibition p38mapk ... See more keywords
Vitamin C prevents epidermal damage induced by PM‐associated pollutants and UVA1 combined exposure
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DOI: 10.1111/exd.14315
Abstract: Particulate matter is suspected to be substantially involved in pollution‐induced health concerns. In fact, ultrafine particles (UFPs) contain polycyclic aromatic hydrocarbons (PAHs) known as mutagenic, cytotoxic and sometimes phototoxic. Since UFPs reach blood circulation from… read more here.
Keywords: vitamin prevents; epidermal damage; exposure; damage induced ... See more keywords