Metformin prevents hypoxia‐induced podocyte injury by regulating the ZEB2/TG2 axis
Sign Up to like & getrecommendations! Published in 2022 at "Nephrology"
DOI: 10.1111/nep.14121
Abstract: Podocytes, a vital component of the glomerular filtration barrier, are vulnerable to various noxious stimuli, including Hypoxic. HIF1α that transduces hypoxic adaptations induces Transglutaminase 2 (TG2), which catalyses cross‐linking of extracellular matrix proteins. In this… read more here.
Keywords: hypoxia induced; metformin prevents; induced podocyte; podocyte injury ... See more keywords