Transcriptional Mutagenesis Prevents Ribosomal DNA Deterioration: The Role of Duplications and Deletions
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DOI: 10.1093/gbe/evz235
Abstract: Abstract Clashes between transcription and replication complexes can cause point mutations and chromosome rearrangements on heavily transcribed genes. In eukaryotic ribosomal RNA genes, the system that prevents transcription–replication conflicts also causes frequent copy number variation.… read more here.
Keywords: duplications deletions; transcriptional mutagenesis; prevents ribosomal; mutagenesis prevents ... See more keywords