Previously undescribed pyridyl-steroidal glycoalkaloids and 23S,26R-hydroxylated spirostanoid saponin from the fruits of Solanum violaceum ortega and their bioactivities.
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DOI: 10.1016/j.phytochem.2021.112656
Abstract: Three previously undescribed pyridyl-steroidal glycoalkaloids, solanindiosides A‒C, one rare 23S,26R-hydroxylated spirostanoid saponin, and two steroidal alkaloid aglycones, solanindins A and B, derived from the acid hydrolysis of solanindiosides A‒C, were isolated from the fruits of… read more here.
Keywords: hydroxy methoxyphenyl; pyridyl steroidal; undescribed pyridyl; methoxy ... See more keywords
Recurrent mutations in topoisomerase IIα cause a previously undescribed mutator phenotype in human cancers
Sign Up to like & getrecommendations! Published in 2022 at "Proceedings of the National Academy of Sciences of the United States of America"
DOI: 10.1073/pnas.2114024119
Abstract: Significance Topoisomerases are crucial for genome maintenance and are targets for several chemotherapeutic agents. While anticancer drugs targeting topoisomerases can lead to secondary malignancies, there have been no descriptions of genetic defects in topoisomerases having… read more here.
Keywords: undescribed mutator; cleavage; topoisomerase; previously undescribed ... See more keywords
Five previously undescribed compounds from Ajuga lupulina Maxim. and their in vitro activities.
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DOI: 10.1080/14786419.2022.2130305
Abstract: A new biflavone (philonotisflavone-3'''-methyl ether), three diterpenes (lupulin G, lupulin H, lupulin I), a new ecdysteroid (ajugasterone E), and four known compounds were isolated from the whole plant of Ajuga lupulina Maxim. Their structures were… read more here.
Keywords: five previously; undescribed compounds; ajuga lupulina; compounds ajuga ... See more keywords
A previously undescribed variant of the confluence of sinuses.
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DOI: 10.5603/fm.a2016.0063
Abstract: An 8-year-old female with a history of chronic headaches and uncertain papilloedema was found to have a variant of the posterior intracranial dural venous sinuses on magnetic resonance imaging assessment of the brain. Magnetic resonance… read more here.
Keywords: undescribed variant; confluence sinuses; confluence; variant confluence ... See more keywords