Effects of endogenous levels of master regulator PrgX and peptide pheromones on inducibility of conjugation in the enterococcal pCF10 system
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DOI: 10.1111/mmi.14339
Abstract: Enterococcal pheromone responsive conjugative plasmids like pCF10 promote horizontal spread of antibiotic resistance genes following induction of plasmid‐containing cells by potential recipients. Transcription of conjugation genes from promoter PQ is inhibited by the master regulator… read more here.
Keywords: regulator prgx; inducibility; prgx; master regulator ... See more keywords
Structural Differences in Complexes between the Master Regulator PrgX, Peptide Pheromones, and Operator Binding Sites Determine the Induction State for Conjugative Transfer of pCF10
Sign Up to like & getrecommendations! Published in 2022 at "Journal of Bacteriology"
DOI: 10.1128/jb.00298-22
Abstract: Peptide pheromones regulate antibiotic resistance transfer in Enterococcus faecalis. Here, we present new data showing that pheromone-dependent regulation of transfer genes is mediated via effects on the structures of complexes between peptides, the intracellular peptide… read more here.
Keywords: transfer; operator binding; transcription; peptide pheromones ... See more keywords