Prickle is phosphorylated by Nemo and targeted for degradation to maintain Prickle/Spiny-legs isoform balance during planar cell polarity establishment
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DOI: 10.1371/journal.pgen.1007391
Abstract: Planar cell polarity (PCP) instructs tissue patterning in a wide range of organisms from fruit flies to humans. PCP signaling coordinates cell behavior across tissues and is integrated by cells to couple cell fate identity… read more here.
Keywords: degradation; cell polarity; isoform; prickle ... See more keywords