Cerebral white matter rarefaction has both neurodegenerative and vascular causes and may primarily be a distal axonopathy.
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DOI: 10.1093/jnen/nlad026
Abstract: Cerebral white matter rarefaction (CWMR) was considered by Binswanger and Alzheimer to be due to cerebral arteriolosclerosis. Renewed attention came with CT and MR brain imaging, and neuropathological studies finding a high rate of CWMR… read more here.
Keywords: matter rarefaction; primarily distal; distal axonopathy; white matter ... See more keywords