Articles with "primary acquired" as a keyword



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Conjunctival cytologic features in patients with unilateral primary acquired nasolacrimal duct obstruction

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Published in 2017 at "International Ophthalmology"

DOI: 10.1007/s10792-017-0471-0

Abstract: PurposeTo evaluate the cytologic features of conjunctival epithelium in patients with unilateral primary acquired nasolacrimal duct obstruction (PANDO) using impression cytology.MethodsTwenty-four patients with unilateral PANDO for at least 1 year were enrolled in this study. The… read more here.

Keywords: patients unilateral; unilateral primary; cytologic features; primary acquired ... See more keywords
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Primary and acquired EGFR T790M-mutant NSCLC patients identified by routine mutation testing show different characteristics but may both respond to osimertinib treatment.

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Published in 2018 at "Cancer letters"

DOI: 10.1016/j.canlet.2018.03.005

Abstract: Primary EGFR T790M mutation is occasionally identified by routine mutation testing in tyrosine kinase inhibitor (TKI)-naive patients with non-small cell lung cancer (NSCLC). We herein aimed to compare the characteristics of primary and acquired T790M… read more here.

Keywords: egfr t790m; acquired t790m; t790m mutant; primary acquired ... See more keywords
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A combinatorial strategy for overcoming primary and acquired resistance of MEK inhibition in colorectal cancer.

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Published in 2020 at "Experimental cell research"

DOI: 10.1016/j.yexcr.2020.112060

Abstract: Compared with traditional chemotherapeutic drugs, targeted therapeutic medicine has the advantages of high efficacy and less toxic side effects. However, in clinical practice for treatment of colorectal cancer, the primary and acquired resistance of these… read more here.

Keywords: medicine; colorectal cancer; acquired resistance; primary acquired ... See more keywords
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Targeting AXL and mTOR Pathway Overcomes Primary and Acquired Resistance to WEE1 Inhibition in Small-Cell Lung Cancer

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Published in 2017 at "Clinical Cancer Research"

DOI: 10.1158/1078-0432.ccr-17-1284

Abstract: Purpose: Drugs targeting DNA repair and cell-cycle checkpoints have emerged as promising therapies for small-cell lung cancer (SCLC). Among these, the WEE1 inhibitor AZD1775 has shown clinical activity in a subset of SCLC patients, but… read more here.

Keywords: acquired resistance; primary acquired; resistance; mtor ... See more keywords
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Recurrence of Primary Acquired Melanosis and Conjunctival Intraepithelial Neoplasia

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Published in 2022 at "Ocular Oncology and Pathology"

DOI: 10.1159/000526985

Abstract: Introduction: The aim of this study was to investigate the frequency of recurrences, time to recurrence, and which patients had a recurrence after treatment of conjunctival intraepithelial neoplasia (CIN), carcinoma in situ, and primary acquired… read more here.

Keywords: primary acquired; pam atypia; recurrence; intraepithelial neoplasia ... See more keywords
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Case of Rapidly Expanding Conjunctival Malignant Melanoma Initially from Primary Acquired Melanosis Diagnosed 14 Years Earlier

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Published in 2021 at "International Medical Case Reports Journal"

DOI: 10.2147/imcrj.s310702

Abstract: Abstract Primary acquired melanosis (PAM) of the conjunctiva is a potentially serious melanocytic lesion that can lead to the development of a melanoma. A 60-year-old woman noticed pigmentation of the conjunctiva of her left eye… read more here.

Keywords: case; melanoma; conjunctival malignant; malignant melanoma ... See more keywords
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Potential biomarkers for distinguishing primary from acquired premature ejaculation: A diffusion tensor imaging based network study

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Published in 2022 at "Frontiers in Neuroscience"

DOI: 10.3389/fnins.2022.929567

Abstract: Introduction Premature ejaculation (PE) is classified as primary and acquired and may be facilitated by different pathophysiology. Brain plays an important role in PE, however, differences in the central neuropathological mechanisms among subtypes of PE… read more here.

Keywords: primary acquired; premature ejaculation; diffusion tensor; ifgtriang ... See more keywords
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Primary and Acquired Resistance against Immune Check Inhibitors in Non-Small Cell Lung Cancer

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Published in 2022 at "Cancers"

DOI: 10.3390/cancers14143294

Abstract: Simple Summary NSCLC accounts for approximately 84% of lung malignancies and the clinical application of ICIs provides a novel and promising strategy. However, approximately 80% of NSCLC patients do not benefit from ICIs due to… read more here.

Keywords: acquired resistance; primary acquired; non small; small cell ... See more keywords
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Primary Acquired Cicatrizing Gastric Outlet Obstruction in Children

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Published in 2022 at "Journal of Indian Association of Pediatric Surgeons"

DOI: 10.4103/jiaps.jiaps_249_20

Abstract: Background: Gastric outlet obstruction (GOO) is a very rare condition in children, when infantile hypertrophic pyloric stenosis is excluded as a cause. Five cases of pediatric GOO were successfully managed at our institute. Materials and… read more here.

Keywords: gastric outlet; stricture; primary acquired; outlet obstruction ... See more keywords