Delta Opioid Receptor Expression and Function in Primary Afferent Somatosensory Neurons.
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DOI: 10.1007/164_2017_58
Abstract: The functional diversity of primary afferent neurons of the dorsal root ganglia (DRG) generates a variety of qualitatively and quantitatively distinct somatosensory experiences, from shooting pain to pleasant touch. In recent years, the identification of… read more here.
Keywords: opioid receptor; somatosensory; primary afferent; dor ... See more keywords
Capsaicin-sensitive cutaneous primary afferents convey electrically induced itch in humans
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DOI: 10.1016/j.neulet.2017.11.061
Abstract: Specially designed transcutaneous electrical stimulation paradigms can be used to provoke experimental itch. However, it is unclear which primary afferent fibers are activated and whether they represent pathophysiologically relevant, C-fiber mediated itch. Since low-threshold mechano-receptors… read more here.
Keywords: itch; stimulation; capsaicin sensitive; primary afferent ... See more keywords
Connexin36 Expression in Primary Afferent Neurons in Relation to the Axon Reflex and Modality Coding of Somatic Sensation
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DOI: 10.1016/j.neuroscience.2018.04.038
Abstract: Electrical coupling mediated by connexin36-containing gap junctions that form electrical synapses is known to be prevalent in the central nervous system, but such coupling was long ago reported also to occur between cutaneous sensory fibers.… read more here.
Keywords: electrical coupling; primary afferent; expression; mice ... See more keywords
High-threshold primary afferent supply of spinal lamina X neurons.
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DOI: 10.1097/j.pain.0000000000001586
Abstract: The spinal grey matter region around the central canal, lamina X, is critically involved in somatosensory processing and visceral nociception. Although several classes of primary afferent fibers terminate or decussate in this area, little is… read more here.
Keywords: lamina neurons; high threshold; primary afferent; afferent supply ... See more keywords
Segmental and descending control of primary afferent input to the spinal lamina X
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DOI: 10.1097/j.pain.0000000000002597
Abstract: Primary afferent input to lamina X is subject to both spinal and supraspinal control being regulated by 5 distinct pathways. read more here.
Keywords: primary afferent; control; afferent input; lamina ... See more keywords
TLR4 mediates upregulation and sensitization of TRPV1 in primary afferent neurons in 2,4,6-trinitrobenzene sulfate-induced colitis
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DOI: 10.1177/1744806919830018
Abstract: Elevated excitability of primary afferent neurons underlies chronic pain in patients with functional or inflammatory bowel diseases. Recent studies have established an essential role for an enhanced transient receptor potential vanilloid subtype 1 (TRPV1) signaling… read more here.
Keywords: trpv1; primary afferent; afferent neurons; colitis ... See more keywords